PLCG2 signaling and genetic resilience in Alzheimer’s disease - Molecular Neurodegeneration Molecular Neurodegeneration - Alzheimer’s disease (AD) is a progressive neurodegenerative disorder characterized by cognitive decline and pathological hallmarks, including amyloid plaques,...

#PLCG2 signaling and genetic resilience in #AlzheimersDisease

Andy P. Tsai, Amara K. Martin, Andrew Mi, Ava E. Yeh, Eduardo Ramirez Lopez, Tony Wyss-Coray #microglia

link.springer.com/article/10.1...

Genetics of PLCG2 expression and splicing relative to Alzheimer’s disease risk - Molecular Neurodegeneration Advances Background PLCG2 is associated with the risk of Alzheimer’s disease (AD) through a rare missense polymorphism, rs72824905 (P522R) as well as a common variant, rs12446759, within a long non-coding RNA ...

Genetics of #PLCG2 expression and splicing relative to #AlzheimersDisease risk

Andrew K. Turner, Kennedy Dotson, Qi Qiao...Steven Estus @uksbcoa.bsky.social @universityofky.bsky.social #genetics

link.springer.com/article/10.1...

In September, we kicked off our #JPND collaboration on #PLCG2 at a meeting in the nice town of #Lille.