Structural plasticity of the coiled–coil interactions in human SFPQ Abstract. The proteins SFPQ (splicing Factor Proline/Glutamine rich) and NONO (non-POU domain-containing octamer-binding protein) are mammalian members of

Discover the dynamic #structural #plasticity of #SFPQ in coiled-coil #interactions, revealing its role in #post-transcriptional regulation within NEAT1 #paraspeckles. PMID:39698821, Nucleic Acids Res 2024 @NAR_Open doi.org/10.1093/nar/...

#Paraspeckles look surprisingly different when you look at them in 3D and using multiple probes. We would be interested to her your ideas on potential functional implications.