Aging-Related Changes in the Injury Response of the Peripheral Nervous System - Neuroscience Bulletin Peripheral nerve injury (PNI) significantly impairs patients’ quality of life, with elderly individuals experiencing particularly severe consequences due to aging-related declines in neuronal injury r...

Cen et al. review key mechanisms & highlight therapeutic targets to improve repair in #aging nerves. #PeripheralNerveInjury #Neuroregeneration
See here: doi.org/10.1007/s122...

Pioglitazone modulates metabolic adaptation and peripheral nerve regeneration after injury - Molecular Neurodegeneration Peripheral nerves have an intrinsic capacity for regeneration after traumatic injury, with Schwann cells (SCs) playing a central role in orchestrating this complex process. Critical components of succ...

#Pioglitazone modulates #metabolic adaptation and peripheral nerve #regeneration after injury

Antonia Seitz, Taylan Özöncü, Daniela Sinske...Sofia Meyer zu Reckendorf @uniulm.bsky.social #PeripheralNerveInjury #schwanncells

link.springer.com/article/10.1...

This review summarizes how #macrophage-driven #neurovascularization supports nerve regeneration after #PeripheralNerveInjury & outlines in vitro #prevascularization, in vivo prevascularization, and in situ stimulation strategies. #scaffolds

#OpenAccess #IJEM: doi.org/10.1088/2631...

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#atocp #physio #orthopedics #trauma #peripheralnerveinjury