This image illustrates a one-tube sample processing strategy for mass spectrometry analysis. It includes a flowchart showing steps: protein extraction, trypsin digestion, and labeling with a 12-plex kit. It depicts two conditions, acidic and basic, for gradient elution. On the right, a mass-to-charge ratio (m/z) data processing graphic is shown.

🚨 New work from the @liresearch.bsky.social Group explores Ti(IV)-IMAC and DiLeu tagging for high-throughput, simultaneous glyco- and phosphoproteomics, enabling deep coverage of model brains with #Alzheimers. https://bit.ly/41DsqVI #PharmSciSky #SciSky #ResearchSky