Great workshop and talk #YingYuan
@mdanderson.bsky.social @fda.gov
on 🔧 backfill strategies in early phase trials including novel BARD covariate-adaptive randomisation strategies allowing dose escalation, backfill and randomisation data to ⏫ efficiency of 🧬 trials #ProjectOptimus #AACR25

FDA Involvement in Dose Optimization Through Project Optimus Drives a Patient-Focused Oncology Pharmacology Career: With D. Ross Camidge, MD, PhD; and Jeanne Fourie Zirkelbach, PhD Drs Camidge and Zirkelbach discuss Zirkelbach's first pharmacokinetics forays and her involvement with reforming dose optimization in drug development.

Great episode Dr Ross Camidge's podcast #HowThisIsBuildingMe with pharmacologist Dr. Zirkelbach (FDA Onc) on drug dev & her focus on #PROs for best outcomes w/fewest AEs

I always learn, but still have questions about #ProjectOptimus
bit.ly/48RlOpz
#LCAM #LCSM #TheRightDose
@itsnotpink.bsky.social