Highlighting the bile acid–#GutMicrobiota crosstalk as a key modulator of the gut–brain axis, regulating #Neuroimmune function, barrier integrity, & #Neurotransmission, with therapeutic implications for neurological & #PsychiatricDisease.
#OpenAccess: doi.org/10.1016/j.ge...
A complex interaction of positive and negative feedback mechanisms linking centers of the limbic system to hypothalamic nuclei explains the adaptive response of the hypothalamic–pituitary thyroid loop in type 2 allostasis resulting from psychosocial stress situations (355, 356, 358, 359). ARC, arcuate nucleus of the hypothalamus; BNST, bed nucleus of the stria terminalis; CRH, corticotrophin-releasing hormone; DA, dopamine; GABA, gamma-aminobutyric acid; LC, locus coeruleus; NAcc, nucleus accumbens; OT, oxytocin; VTA, ventral tegmental area.
Complex networks linking #amygdala, #BNST & #hypothalamus mediate type 2 #Thyroid_Allostasis in #PTSD (post-traumatic stress disorder) & #PsychiatricDisease
www.livivo.de/doc/M28775711
pubmed.ncbi.nlm.nih.gov/28775711/
doi.org/10.3389/fend...
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