Frontiers | Rab21 recruits EEA1 and competes with Rab5 for Rabex-5 activation Rab5 is a key regulator of early endosomal traffic and fusion. It shares its localization and guanine nucleotide exchange factor Rabex-5 with the less charac...

New publication about how #Rab21 regulates early endosomal size by recruiting EEA1 to the endosomes via a pathway parallel to Rab5 and highlight Rabex-5’s critical role in Rab21 and #Rab5 cross-regulation.
With Francisco Yanguas & Cinzia Progida from @biovitenskap.bsky.social

A new role of RAB21 and VARP in autophagy and autophagic exocytosis of ATP Autophagy has been implicated in various cellular processes, including non-conventional secretion. Our previous findings suggest that ATP is loaded into amphisomes and secreted upon autophagy stimu...

A new role of #RAB21 and #VARP in #autophagy and autophagic #exocytosis of #ATP
#VAMP7
www.tandfonline.com/doi/full/10....