⭐ #NARBreakthrough! ⭐
🧬 New study uncovers how #RNAstructures control stochastic exon selection in Dscam1 genes. #Balancer RNA structures and a #multi-subunit RNA architecture coordinate spatial and temporal splicing 🔬✨
Read the full article here: doi.org/10.1093/nar/...
#AlternativeSplicing

🧬 Mind-blowing discovery, right? The idea that there's a whole new class of life forms—these "Obelisks"—hiding in our bodies is wild! 🤯

Let me know in the comments! 👇

#ObelisksDiscovery #NewLifeForm #MicrobiomeMystery #RNAStructures #ScienceBreakthrough

Scientists Discover "Obelisks": Mysterious New RNA Structures Found in the Human Body 🦠🧬 #ObelisksDiscovery #NewLifeForm #MicrobiomeMystery #RNAStructures #ScienceBreakthrough #biology
youtu.be/620P-80vwbo

Redirecting

Modeling #RNAstructures and RNA–protein complexes is advancing via methods capturing conformational heterogeneity and integrate experimental restraints, helpful for understanding viral RNA elements and protein interactions.
📄 https://doi.org/10.1016/j.sbi.2025.103137
👤 EVBC member: Janusz Bujnicki

Discovery of functional factorless internal ribosome entry site-like structures through virome mining Author summary The simplest eukaryotic protein synthesis mechanism to date is found within an internal ribosome entry site (IRES) from the dicistrovirus family. The IRES adopts an RNA structure that can directly bind to and manipulate the ribosome to initiate translation from a non-AUG codon. Using a bioinformatics pipeline, we identified >4700 viral genomes that have IRES-like structures, highlighting conserved elements and atypical genome arrangements that include an embedded IRES within viral open reading frames. Moreover, we identified IRES-like structure in other viral families suggesting widespread adoption of this viral translation strategy. This study highlights the diverse viral strategies utilizing RNA-driven mechanisms.

Virome-wide mining discovers factorless IRES-like elements enabling cap-independent translation across viruses.
#RNAstructures #ViromeMining #IRES
👤EVBC: Artem Babaian
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