In starvation, both step-up deiodination (via D1 and D2) and thyroid-stimulating hormone (TSH) release are reduced, leading to low-T4 and low-T3 constellations. rT3 concentrations may be increased. Black and red arrows indicate the direction of change from normal, homeostatic conditions in fed state.
Low #T3 and high reverse T3 mark the endocrine signature of #Thyroid_Allostasis in #starvation. #rT3 #Leptin
www.livivo.de/doc/M28775711
pubmed.ncbi.nlm.nih.gov/28775711/
doi.org/10.3389/fend...
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