GABAergic Inhibition from the Nucleus Tractus Solitarius to Ventrolateral Medulla Phox2b Neurons Modulates Central Respiratory Chemoreflex and Ventilatory Homeostasis - Neuroscience Bulletin Central respiratory chemoreception is a vital homeostatic mechanism maintaining arterial blood gas levels. Central respiratory chemoreceptors in the retrotrapezoid nucleus (RTN) and nucleus tractus so...

Shao et al. demonstrate that activation of #NTS GABAergic neurons suppresses #Phox2b-expressing #RTN neurons, attenuates CO₂-evoked ventilatory responses, and induces hypoventilation. See here: doi.org/10.1007/s122...
#RespiratoryControl #Chemoreception #NeuralCircuits

Prenatal exposure to synthetic cannabinoid alters breathing and cardiovascular health in rats Prenatal exposure to the synthetic cannabinoid WIN caused sex-specific respiratory control changes, fragmented sleep, and heightened cardiovascular risks in rats, highlighting potential long-term health concerns for offspring from cannabis use during…

Prenatal exposure to the synthetic cannabinoid WIN caused sex-specific respiratory control changes, fragmented sleep, and heightened cardiovascular risks in rats, highlighting potential long-term… #PrenatalExposure #SyntheticCannabinoid #BreathingHealth #CardiovascularHealth #RespiratoryControl