.@METUPorg #sabcs16 YIR
THRILLED to see how few left prior to mets session and how many stayed - much better than #sabcs15!!
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Hashtag
#SABCS15
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#SABCS15 highlights cont... @bethfairchildnc @LeslieFalduto @Majormac1 @SpiveySandra @anneloeser @karunajaggar
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My highlight of #SABCS15: @jenniegrimes @CultPerfectMoms @Nikhilwagle @corrie_painter @Groz_P @a4breastcancer @AmazzoneFuriosa continued..
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Paloma 3 pre & post-meno patients fulvenstrant + palbo incr PFS by about 6 mo. #SABCS15
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People flooding out for the mets year in review. WTF. Guess since we're #dyingforacure we don't matter. #stageivneedsmore #SABCS15
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Denosumab (prolia) in early stage ER + on AIs not only decr fracture but also recurrence #SABCS15 #YearInReview
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PAK1 bad actor, may drive mets. #SABCS15 #YearInReview
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Can cfDNA detect mutations and emerging resistance and allow change in therapy that will be clinically significant? #SABCS15
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CfDNA detected in 90% of metastatic patients #SABCS15
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"Breast cancer genomics is chaotic" -as is the effect on patients' lives #SABCS15
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Loss of PTEN leads to resistance to a PI3K I inhibitor. #SABCS15
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"Can we not use our power to push for sharing of data" #SABCS15
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Love it when the oncs cant pronounce these drugs either "let's just call it BKM!" #SABCS15
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@jenniegrimes @teamoncology for those of us metastatic we need a "lifer" or "dying for a cure" badge! #lifer #SABCS15
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Decision re surgery: surgeons strong opinion 11%, partners supportive, kids have strong opinion- finally can tell mom what to do! #SABCS15
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Those with recurrent breast cancer or male breast cancer have a higher rate of germline mutations and should be offered screening #SABCS15
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Option of 15 days (3 weeks) XRT viable - certainly would be better for patients! #SABCS15
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Should be we adding palbo to anastrazole in neoadjuvant tx of ER + stage 2/3? #SABCS15
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Eric Weiner: it's all about quality of life #SABCS15
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Tell my bladder that tamoxifen is worse than anastrazole! #SABCS15
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Joint pain with anastrazole: yup. But being alive trumps creaky joints #SABCS15
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Few studies on landscape of MBC. As we keep saying #stageivneedsmore #SABCS15
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BELLE2: combo fulvenstrant & buparlisib@after progress on AI. PFS full pop assumed xtra 2.5mo, got 1.9 - no wonder depression s/e.
#SABCS15
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Liquid biopsy HOT at this meeting! Maybe should buy stock??#SABCS15
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What's the optimal assay? Big center: exome sequencing. Real world: proxy for mutational load #SABCS15
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Those identified poor prog could be fast tracked in trial or given compassionate use for possible drugs in phase 1/2 #SABCS15
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Genomic analysis may identify those with poor prognosis: ESR1 and mutational load. #SABCS15
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Sequence to develop patient specific vaccine - ripe for research #SABCS15
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