I'm not HER2+ and I don't have #brainmets but when I heard these results at #SABCS19 I cried, and I cried again Friday when the @FDAOncology approved #tucatinib. I cried because my HER2+ friends now have another option. #bcsm
It was beautiful, that first @GRASPtweets poster walk thru inlay #sabcs19 - new advocates, experienced advocates, oncologists, researchers all learning from one another. #bcsm
I truly believe that #Advocacy is saving my life, not only because of the #Research we advocate for, but because of the friends I’ve made and the sense of purpose it has given me. #MetastaticBreastCancer #bcsm #SABCS19
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.@SABCSSanAntonio what happened to the presentations?? Some of us were going to refer back to them and watch the ones we missed because human cloning isn’t ready for prime time yet! #SABCS19 #oncoalert #bcsm #ICantBeInStarsAtNightAndHemisFairAtTheSameTime
@GRASPtweets #GRASPcancer was my highlight of #SABCS19 (that and trying to catch @itsnot_pink on top of the twitter influence charts 😂). @christeeny513 and @itsnot_pink are incredible women and friends. #bcsm
Ok, I *really* can’t count 😂 Finally, a trial for #TNBC #MBC Dr Hurvitz mentioned using sacituzamab govitecan (actually I just forgot to add this photo to last tweet). And with this, my tweeting from #SABCS19 is complete. Thanks to all who followed and RTed. #bcsm #oncoalert
3/3 (I can’t count!) #TNBC #MBC sacituzumab, this time with govitecan (NOT same ADC as DS8201), targeting Trop2 which is expressed in TNBC. A third of people responded.#SABCS19 #oncoalert #bcsm
2/2 #TNBC #MBC Dr Hurvitz mentioned this ⬇️ but significant adverse events of diarrhea and rash l, although overall response rate of 73% was good #SABCS19 #oncoalert #bcsm
Ok, I’m standing in the line at @Starbucks at SAT. #TNBC #MBC at #SABCS19 - not much. #IMpassion130 was reported at #ASCO19. Slides here ⬇️ 1/2 (or maybe 3?) #oncoalert #bcsm
Not as much info on #TNBC #MBC but I’ll tweet out some of what Dr Hurvitz said after I get the the airport. It’s a wrap for #SABCS19
But such great results a with DS8201 in #DESTINY dot come with it a price - 2.2% had grade 5 lung disease as a result. Grade 5 is death. #SABCS19
#DESTINY was another exciting trial for #HER2 with DS201 showing exciting improvement in PFS in heavily pretreated patients. Dr Hurvitz: “I’ve never seen a waterfall plot as@exciting as this “ #SABCS19 #oncoalert #bcsm
I’m not #HER2. I don’t have #brainmets. The results from #HER2Climb and the hope it provides to my friends with HER2+ disease made me cry tears of joy. #SABCS19 #oncoalert #bcsm @SeattleGenetics
For #HER2 especially with #brainmets the HUGE news is #HER2climb using @SeattleGenetics Tucatinib. Huge because the trial included untreated/active brain mets and these patients had amazing results. 1/2 #SABCS19 #oncoalert #bcsm
And for those with a PIK3CA mutation, alpelisib provides new treatment options and hope #SABCS19 #oncoalert #bcsm #ERpos #PIK3CA
What about CDK 4/6 inhibitors in ER+/HER2+ disease? @stolaney1 has shown improvement with triplet therapy that included endocrine blockade with a SERD, HER2 targeted therapy and a CDK4/6 inhibitor. #ERpos #HER2 #SABCS19 #oncoalert #bcsm
Young-PEARL study (1st presented at #ASCO19) showed CDK4/6 + AI (+ ovarian suppression as these were young women) inhibitors were superior to capecitabine #SABCS19 #oncoalert #bcsm #ERpos
Dr Hurvitz: we are not doing harm to our patients by using CDK 4/6 inhibitors instead of chemo. Overall response rates with CDK 4/6 are 50%+ #SABCS19 #bcsm #oncoalert
Men get breast cancer. Men get #MBC. So happy to have met @malefitness at #SABCS19 www.curetoday.com/conferences/sabcs-2019/a... via @cure_magazine
What a pleasure to meet this #OncologyFellow and #YoungInvestigator from @fredhutch. @poorni_manohar is doing great work that takes into account the financial cost of diagnosis and treatment. She will be a powerhouse, I’m sure. #SABCS19 #oncoalert #bcsm
Congratulations to Ginny Mason @IBCResearch and partners in research @SusanGKomen Krissa Smith and the Milburn Foundation for this scoring system for #Inflammatory breast cancer. #SABCS19 #bcsm
My two favorite Sandis-with-an-I: @SpiveySandra and @sandisues. Both are powerhouses in #Advocacy. #SABCS19 #bcsm
.@MarinaRKaplan Your poster was well received and generated some meaningful conversations with oncologists. I just wish you could have been here to present it. #livermets #SABCS19 #bcsm #WhatWeWantOurOncologistsToKnow
Clinicians at #SABCS19: what’s the ICD-10 code for hand cramp, non dominant, secondary to tweeting? #SABCS19 #oncoalert #bcsm #JuliaWillStillBeatMeAsTopInfluencer
THIS ⬇️ is how hard these women worked on #GRASPcancer @GRASPtweets. Passed out in the @LillyPad sponsored @abreastcancer #Advocate lounge at #SABCS19. ❤️ @christeeny513 @itsnot_pink #bcsm
Response rates and even OS were better in the oral group, and some side effects were better - but others, like 🤢 were worse. I wonder about the #FinancialToxicity How much would the oral paclitaxel cost?? #SABCS19 #oncoalert #bcsm
Study done in South and Central America. Oral drugs (if not prohibitively $$$) would be a boon in the developing world (and everywhere, because we’d all rather take a pill) Frustrating to us patients is that those with #brainmets were excluded #SABCS19 #oncoert #bcsm