SBGrid's eLife paper received a citation in February from Anthony Kossiakoff from The University of Chicago in @pnas.org : Conformational ensembles of the magnesium channel CorA reveal structural basis for channel gating.
Read more here: buff.ly/3Oawrum
#SBGrid #ScienceMatters
New Title Alert: vossvolvox- a C++17 command-line tools for analyzing molecular structures, specifically for computing volumes, channels, cavities, and tunnel geometry from various molecular input formats.
Learn more here: buff.ly/0ff33pF
#SBGrid #SBGridSoftware
SBGrid's eLife paper received a citation in February from Alireza Ghanbarpour from Washington University School of Medicine in St. Louis, in @Nature: Bacterial immune activation via supramolecular assembly with phage triggers.
Read more here: buff.ly/vgiNzUl
#SBGrid #ScienceMatters
SBGrid's eLife paper received a citation in February from Christopher Garcia from @stanforduniversity.bsky.social School of Medicine in @science.org: Structural ontogeny of protein-protein interactions.
Read more here: buff.ly/BPRhfUL
#SBGrid #ScienceMatters
SBGrid's eLife paper received a citation in February from Eric Fischer from @danafarber.bsky.social in @natchembio.nature.com
High-throughput ligand diversification to discover chemical inducers of proximity.
Read more here: buff.ly/Z9db5GU
#SBGrid #StayConnected
In case you missed Joshua Mitchell webinar featuring Open Force Field Initiative, it is now available in our YouTube channel.
More here: buff.ly/6tzRrM8
#SBGrid #Webinars #ScienceMatters
Member News: SBGrid member Andrew Kruse, professor of biological chemistry & molecular pharmacology in the Blavatnik Institute at HMS is featured in The Harvard Gazette for his discovery offering hope for patients with hard-to-treat heart disease.
Read more here: buff.ly/ZZjaGtZ
#SBGrid #Members
SBGrid's eLife paper received a citation in February from Elizabeth Wright from @uwmadison.bsky.social in @natprot.nature.com : Integrated fluorescence light microscopy-guided cryo-focused ion beam-milling for in situ montage cryo-ET.
Read more here: buff.ly/EGZomRA
#SBGrid #ScienceMatters
New Title Alert: mBER-open- is a protein design framework for antibody binder design that leverages structure templates and sequence conditioning in backpropagation-based design through AlphaFold-Multimer.
Learn more here: buff.ly/59LkTAm
#SBGrid #SBGridSoftware
SBGrid's eLife paper received a citation in February from James Berger from @jhu.edu School of Medicine in @natcomms.nature.com : Supercoiled DNA recognition and cleavage control in topoisomerase VI.
Read more here: buff.ly/tKmGHHK
#SBGrid #ScienceMatters
SBGrid's eLife paper received a citation in February from John Pascal from Université de Montréal (University of Montreal) in @natcomms.nature.com : PARP1-HPF1 structure and dynamics on nicked DNA suggest a mechanism for acute and localized ADP-ribosylation.
Read more here: buff.ly/VbygZD2
#SBGrid
New Title Alert: easymode- a collection of general pretrained networks for cellular cryoET.
Learn more here: buff.ly/mLbcUbZ
#SBGrid #SBGridSoftware
News Alert: We've updated SBGrid's primary citation to our 2024 Acta Crystallographica paper. We would be grateful if you could use this reference in future manuscripts, preprints, and related work where appropriate.
Read it here: buff.ly/RQ0Ybpx
#SBGrid #Citation
Technical Notes: This month's software push includes updates to Ais, AlphaFold3, Boltzgen, Bowtie2, CellProfiler, ChimeraX, CryoMaskR, CryoSPARC-tools, Foldseek, IsoNet2, Protenix, RDKit, and upside2-md.
More here: buff.ly/SHUsfWz
#SBGrid #Software #StructuralBiology
Join our software webinar on March 10th to hear from Joshua Mitchell from the Open Molecular Software Foundation on Open Force Field Initiative. '
Tues, March 10, 2026 12:00PM ET
Josh Mitchell
Science Communicator, Open Force Field
Register here: buff.ly/YVCdTmr
#SBGrid #StructuralBiology
SBGrid's eLife paper received a citation in February from Woonghee Lee from University of Colorado Denver in Journal of Biological Chemistry: Modernizing Biomolecular NMR: the POKY Suite.
Read more here: buff.ly/7ys6qCM
#SBGrid #ScienceMatters
Meharry Medical College student Mudiare Ikoba chose to highlight a publication in Nature Communications from the lab of Ed Twomey of The Johns Hopkins University School of Medicine: How signals move through the brain.
Read more here: buff.ly/sDiLwk5
#SBGrid #StructuralBiology
Fisk University student Cariuna Ellison's highlight features a paper from Fengbin (Jerry) Wang of University of Alabama at Birmingham that appeared in Emerging Topics in Life Sciences: Electric Bacteria: Biological “Power Cords”
Read more here: buff.ly/M2lX8Ct
#SBGrid #cryoEM #Bacteria
SBGrid's eLife paper received a citation in January from Dhirendra Simanshu at Frederick National Laboratory for Cancer Research in @nature.com Communications
Read more here: buff.ly/YynO1k1
#SBGrid #StayConnected #ScienceMatters
SBGrid's eLife paper received a citation in January from @drennanlab.bsky.social at @mit.edu in @nature.com : A highly dynamic mononuclear non-heme iron enzyme for the two-step isonitrile biosynthesis.
Read more here:https://buff.ly/t8tGieS
#SBGrid #StayConnected #ScienceMatters
SBGrid's eLife paper received a citation in January from Jean-Philippe Julien at @sickkidsto.bsky.social in @Nature Magazine Communications: A stabilized tandem antigen chimera that elicits potent malaria transmission-reducing activity.
Read more here: buff.ly/AnmiV5Y
#SBGrid #ScienceMatters
New Title Alert: ThermoMPNN- is a graph neural network (GNN) designed to predict changes in stability for protein point mutants using transfer learning.
Learn more here: buff.ly/cXIXkW8
#SBGrid #SBGridSoftware #StructuralBiology
SBGrid's eLife paper received a citation in January from @awehenkel.bsky.social , Pedro M. Alzari, and Ahmed Haouz from @pasteur.fr in ASM Journals: Mechanistic insights into SteAB regulation of cell wall hydrolase RipA in Mycobacterium tuberculosis.
Read more here: buff.ly/tY3MqKF
#SBGrid
New Title Alert: Slabify- is a command-line tool designed for the automatic segmentation of lamella slabs in cryo-electron tomography (cryo-ET) volumes.
Learn more here: buff.ly/fVsKsOS
#SBGrid #SBGridSoftware
New Title Alert: MagCalEM- Accurate magnification determination for cryoEM determining the correct magnified pixel size of single-particle cryoEM micrographs is necessary to maximise resolution and enable accurate model building.
Learn more here: buff.ly/vuCrtWR
#SBGridSoftware #SBGrid
New Title Alert: LASErMPNN- is an all-atom ligand-conditioned protein sequence design and sidechain packing model that accounts for the presence of small molecules, including hydrogens.
Learn more here: buff.ly/cZcOmpC
#SBGridSoftware #SBGrid #StructuralBiology
SBGrid's eLife paper received a citation in January from Eric Girard at IBS Grenoble in @angewandtechemie.bsky.social: Action of Crystallophore and Imaging-Crystallophore Enhances the Production and Imaging of Protein Crystals.
Read more here: buff.ly/Cjk6R1c
#SBGrid #ScienceMatters #StayConnected
New Title Alert: IsoNet2- a deep-learning software package for simultaneous missing wedge correction, denoising, and CTF correction in cryo-electron tomography reconstructions using a deep neural network trained on information from the original tomogram(s).
Learn more here: buff.ly/2ZlZInD
#SBGrid
New Title Alert: ImmuneBuilder- is a high-performance deep learning framework developed by the Oxford Protein Informatics Group (OPIG) specifically for predicting the 3D structures of immune receptor proteins.
Learn more here: buff.ly/wCaRFLp
#SBGrid #SBGridSoftware #StructuralBiology
New Title Alert: Foundry- is a unified framework for protein design that provides tooling and infrastructure for using and training models.
Learn more here: buff.ly/2TdjDOE
#SBGrid #SBGridSoftware #StructuralBiology
