Modeling early gastrulation in human blastoids with DNA methylation patterns of natural blastocysts Xie et al. generate 4CL blastoids with morphology, transcriptional profiles, and DNA methylation patterns similar to those of blastocysts while maintaining gene imprinting and showing potential for po...

People should be more discerning when using the term gastrulation in #SCEMs as in this report from Cell Stem Cell www.cell.com/cell-stem-ce... there is no evidence for #gastrulation.

Nuffield Council on Bioethics sets out proposals to bolster governance of stem cell-based embryo models including a call for legislation to ensure that research does not cross ethical ‘red lines’ - Nu... The Nuffield Council on Bioethics (NCOB) has published proposals for the governance of research using stem cell-based embryo models (SCBEMs).

This is an important step, a well crafted and thought out proposal on #SCEMs
shorturl.at/kgAgr
These discussions, together with an increase in the standards of the field will allow this research to develop the potential many of us believe has.
#Nuffield #StemCells #Bioethics #Embryos