Overcoming a false-positive mechanism in RapidFire MRM-based high throughput screening False-positives plague High Throughput Screening in general and are costly as they consume resource and time to resolve. Methods that can rapidly identify such compounds at the initial screen are ther...

Overcoming a false-positive mechanism in RapidFire MRM-based high throughput screening #SLASDiscov www.slas-discovery.org/article/S247...

#FGF9 #Senescence #Senomorphic

Secretome (1204 proteins) screening on Senescent features (p21 Cell area Nuclei area) of primary👤lung fibroblast -/+Etoposide

Inducer▶️IFNα5/14/16/17
Inhibitors▶️FGF4/9/20

FGF9⏬SASP in normal/IPF lung fibroblast

#SLASDiscov 2025
www.slas-discovery.org/article/S247...