Benzo[a]pyrene (BaP) worsens atherosclerosis via SPP1-driven macrophage inflammation and lipid dysregulation. Integrative omics with cellular validation reveal SPP1 as a potential target in pollution-related vascular disease. #Atherosclerosis #EnvironmentalHealth #SPP1
doi.org/10.1016/j.vp...

Researchers use #SingleCellRNAseq to map #obesity-related #glomerulopathy, revealing reduced immune cells, #SPP1 upregulation in T/B cells, altered metabolic & inflammatory pathways, and key podocyte–parietal epithelial interactions.

#OpenAccess: doi.org/10.1016/j.ge...

This study identifies SPP1+ #macrophages as regulators of #DiscDegeneration, expanding in diseased discs, driving matrix loss via #SPP1, while #exosome-directed #SPP1 blockade restores autophagy and offers a promising therapeutic path.

#OpenAccess: doi.org/10.1016/j.ge...

youtu.be/kMI0eg_0ztg
#GirlsFrontline #DollsFrontline #ドールズフロントライン #SPP1

Girls' Frontline: SPP-1 Profile.

People only care because she fires underwater.

Link in the replies!

#GirlsFrontline #DollsFrontline #ドールズフロントライン #SPP1