🆕 Phylogenetic analysis of the 2025 #SUDV outbreak shows it clusters with the 2012 Luwero strain, not the 2022 outbreak.

Suggests independent spillover event. Strengthening genomic surveillance is key to understanding spillover risks.

virological.org/t/near-real-...

Cryo-EM structure of Sudan ebolavirus glycoprotein complexed with its human endosomal receptor NPC1 Communications Biology - The structural basis for human NPC1 recognition by Sudan ebolavirus provides key insights into receptor binding, cell entry, tissue tropism, and host range, not only for...

This study reveals that Sudan ebolavirus glycoprotein binds to the human NPC1 receptor ~9 times more strongly than Ebola virus glycoprotein. Identifying 4 key residues that differ in binding from EBOV. #virology #EbolaVirus #SUDV www.nature.com/articles/s42...