Pathogenic proteotoxicity of cryptic splicing is alleviated by ubiquitination and ER-phagy RNA splicing enables the functional adaptation of cells to changing contexts. Impaired splicing has been associated with diseases, including retinitis pigmentosa, but the underlying molecular mechanis...

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#IBC2

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👨🏻‍🔬 @prieto-garcia.bsky.social
doi.org/10.1126/scie...