Smallpox Comes to the Americas (1507-1524) — Indigenous Mexico For at least 15,000 years, the people of the Americas – for the most part – had been isolated from the entire Old World (which included Europe, Asia and Africa). This meant that many diseases which ha...

Learn about the first smallpox epidemic as it raged through the Americas and helped to destroy the Aztec/Mexica Empire. Why were the Indigenous people so vulnerable?

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www.indigenousmexico.org/articles/sma...