#DILI #InSilicoToxicology #NAMs #DrugSafety #PBK #BSEP #QSP #SystemsToxicology

A systems toxicology approach implicates post-transcriptional regulatory networks in reproductive defects from PFAS exposure Abstract. Per- and polyfluoroalkyl substances (PFAS) are highly persistent in the environment and widespread in consumer products, environmental media, and

🚨 New paper alert from our lab! Using model system and in vitro approaches, we demonstrate that PFAS, likely due to their physicochemical properties as surfactant, disrupt liquid-like condensates critical for reproduction. Link: academic.oup.com/toxsci/advan...

#PFAS #Toxicology #SystemsToxicology