Highly cited article on #IBD!

This study reveals that #TL1A promotes TGF-β1-mediated intestinal fibroblast activation, proliferation, and #Collagendeposition, likely through upregulation of the TGF-β1/Smad3 signaling pathway. #medsky

Read more: link.springer.com/article/10.1...

DEFINE_ME

More #TL1A inhibitor data this week, with results of duvakitug mAB for #UlcerativeColitis; and #CrohnDisease Sanofi
lnkd.in/ejZrZyvU

This class of drug has potential to reverse fibrosis;
www.mucosalimmunology.org/article/S193...