An integrative approach to rational engineering of dengue virus-like particles Using multiscale simulations and experimental validation, this study uncovers how envelope protein-lipid interactions govern dengue virus-like particle (VLP) stability, secretion, and immunogenicity. ...

Our latest work in Cell Reports Physical Science,
We engineered dengue virus-like particles with enhanced secretion & stability — advancing next-gen VLP-based dengue vaccine development.
#Dengue #VaccineDesign #VirusLikeParticles
www.cell.com/cell-reports...

Breakthrough in next-generation polio vaccines – BioNews Central Researchers are advancing a safer and more affordable polio vaccine by utilizing virus-like particles that mimic the poliovirus's outer protein shell without containing any infectious material. ...

Researchers are advancing a safer and more affordable #PolioVaccine by utilizing #VirusLikeParticles that mimic the #poliovirus 's outer protein shell without containing any #infectious material.
#Polio #VaccineSafety #ImmuneResponse

Engineered virus-like particles evolve for superior gene delivery efficiency Researchers developed a barcoded directed evolution system for engineered virus-like particles (eVLPs), creating a fifth-generation (v5) eVLP with enhanced production, transduction, and gene-editing e...

Engineered virus-like particles evolve for superior gene delivery efficiency ✨🔬🧬 www.news-medical.net/news/2024111... #GeneEditing #Biotechnology #VirusLikeParticles #GeneTherapy #Innovation #Medical #Therapeutics #Bioengineering #Science @naturebiotech.bsky.social

New Quartet nanocage vaccine shows promise against coronavirus variants Researchers have developed a novel vaccination approach using Quartet nanocages that display receptor-binding domains (RBDs) from different sarbecoviruses, showing enhanced immune responses and potent...

New Quartet nanocage vaccine shows promise against coronavirus variants 🦠🔬💉 www.news-medical.net/news/2024050... #Quartet #Nanocages #Vaccine #SARSCoV2 #Coronavirus #Pandemic #Nanotechnology #VirusLikeParticles @natureportfolio.bsky.social