Got my first appointment with an 'internationally acclaimed' researcher/neurologist in London UK, towards the end of May. This could be massive!! #NewmuneSystemPlease #aHSCT #BringIt (with bells on please!)
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#aHSCT
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My first #AHSCT patient: 25 years of NEDA-3. No relapses, no MRI activity, improved EDSS, no DMTs.
75% of RRMS patients treated with BEAM+ATG at CReSM San Luigi (Orbassano) are in #NEDA-3.
This opportunity must reach more patients. AHSCT needs to be a research priority.
🔗 Visit curems.net
#AHSCT #MS
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About this, the story is nothing new. Tried 2 DMTs, and I sent out a cry for help looking for the #aHSCT. That email blast to researchers circled back to a doctor in portugal who had performed the procedure in Coimbra. It was thanks to her that I had that chance.
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Thank you to @gavingiovannoni.bsky.social for writing this over 2 years ago. Thought provoking and will contribute to my discussions with my neuro.
#MS #AHSCT #CAR-T-Cell
gavingiovannoni.substack.com/p/ahsct-vs-c...
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Next MRI's booked in for pre-empting #AHSCT treatment for #MS. I doubt I'll meet the eligibility criteria, but let's allow #CharingCross Hospital to make that decision. Happy Christmas everyone, let 2026 bring stem cell transplantation! 🙏🏼😊😂
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Enquiry about #AHSCT, #PIRA and arriving at a #HyperbaricOxygen Chamber over the next 72hrs. Oh yeah and I'll work a little bit too! Busy week ahead with many questions and hopefully some answers as well #MS
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New review out
AHSCT remains the most potent disease-modifying therapy for selected patients with rapidly progressive #dSSc and ILD
🔸RCT evidence, immune reconstitution, long-term outcomes, and future directions
🔗 acrjournals.onlinelibrary.wiley.com/doi/10.1002/ac…
#Rheumatology #SSc #AHSCT #ILD
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Mariottini et al., 2025: "Autologous haematopoietic stem cell transplantation affects long-term progression independent of relapse activity in aggressive multiple sclerosis: a comparative matched study"
New JNNP study: In aggressive #RRMS, AHSCT greatly reduced PIRA: 10% over 10 years vs 49% in patients moving from natalizumab to other DMTs. Findings suggest #AHSCT may target the silent, smoldering processes that drive MS progression.
🟢More on AHSCT and MS at curems.net
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CureMS.net turns one!
🎉 curems.net turns one!
In 12 months:
🟢 40% Italian, 60% international readers
🟢 1,250+ contacts from 56 countries
🟢 152 scientific papers cited
🟢 Biweekly updates
CureMS.net is becoming a key resource on #AHSCT for patients and professionals. Thanks to all who support and to all the readers! #MS
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An analysis by curems.net, which compiles comparative studies (including Kalincik’s), shows that no DMT is superior to AHSCT, either in clinical or radiological outcomes.
Kalincik et al. ( #ECTRIMS 2025) compared #AHSCT (152 pts) vs anti-CD20 (Ocrelizumab 752, Rituximab 107).
#AHSCT showed better ARR and EDSS improvement, with no difference in worsening. No DMT outperforms AHSCT in #RRMS.
🟢 Highlights curems.net/benefits-of-...
Poster core.melbourne/wp-content/u...
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AHSCT distribution in MS (RRMS versus other MS forms), per year (1995-2023): EBMT-ADWP registry data. Boffa & Genchi et al., 2025. MSJ.
Boffa & Genchi et al. review on aggressive #MultipleSclerosis (EBMT registry, 2,200 pwMS): #AHSCT should be considered early in poor prognosis cases, including DMT non-responders & treatment-naïve with rapid progression.
🟢 More info: journals.sagepub.com/doi/10.1177/...
🔵 Visit curems.net
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Day 9 of #aHSCT and I'm hooked up to the apheresis machine. I'm on course to hit the required 2,000,000 stem cells #multiplesclerosis #ms
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"PwMS after aHSCT: dealing with medical issues and neurological expectations": this study implemented by the EBMT Patient Advocacy Committee is ongoing! Results will be presented at the 49th EBMT Annual Meeting. #EBMT #MultipleSclerosis #aHSCT
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