Data showing that TMEM55A-mediated PI5P signalling regulates #alphacell actin depolymerisation and #glucagon secretion #Islets #DiabetesResearch #Endocrinology

TMEM55A-mediated PI5P signalling regulates alpha cell actin depolymerisation and glucagon secretion - Diabetologia Aims/hypothesis Diabetes is associated with the dysfunction of glucagon-producing pancreatic islet alpha cells, although the underlying mechanisms regulating glucagon secretion and alpha cell dysfunct...

RNA-seq analysis and experimental exploration show that TMEM55A-mediated PI5P signalling regulates #alphacell actin depolymerisation and #glucagon secretion. #islets, #diabetes link.springer.com/article/10.1... 🔓 @xiongliu.bsky.social @bcellorg.bsky.social