#alteplase hashtag - Bluesky

@therapies.bsky.social

1 month ago

Angioedema reported with tissue plasminogen activators: A need to communicate on bradykinin- and histamine-mediated mechanisms Angioedema reported with tissue plasminogen activators: A need to communicate on bradykinin- and histamine-mediated mechanisms

Pharmacovigilance

Angioedema reported with tissue plasminogen activators: A need to communicate on bradykinin- and histamine-mediated mechanisms

#Angioedema #Tissu #Plasminogen #Activator #Alteplase #Adverse #Effects

www.em-consulte.com/article/1795...

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@rcatanho.bsky.social

4 months ago

Intra-Arterial Alteplase After Successful Endovascular Reperfusion in Acute Stroke This randomized clinical trial compares the effects of intra-arterial alteplase treatment vs standard treatment on functional outcomes in patients with acute, anterior-circulation, large-vessel occlus...

En pacientes con ictus agudo por oclusión de un gran vaso de la circulación anterior que consiguen una reperfusión endovascular exitosa por trombectomía mecánica la alteplasa intrarterial mejora la probabilidad de un resultado excelente a los 90d #alteplase #stroke jamanetwork.com/journals/jam...

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@rcatanho.bsky.social

5 months ago

Intra-Arterial Alteplase After Successful Endovascular Reperfusion in Acute Stroke This randomized clinical trial compares the effects of intra-arterial alteplase treatment vs standard treatment on functional outcomes in patients with acute, anterior-circulation, large-vessel occlus...

En pac c/ictus agudo por oclusión de grandes vasos de la circulación ant que alcanzaron reperfusión endovascular exitosa por trombectomía mecánica, uso de alteplasa intraarterial resulta en una mayor probabilidad de variables excelentes a los 90d #alteplase #stroke jamanetwork.com/journals/jam...

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Mark Goldberg 🧠

@markgoldbergmd.bsky.social

1 year ago

Bar graph showing similar 90-day mRS outcomes for stroke patients treated with IV pro-UK vs alteplase.

PROST-2 trial: IV pro-urokinase non-inferior to IV #alteplase for acute #stroke patients <4.5 hr, no thrombectomy.

Pro-UK was last seen in clinical trials 25 years ago as intra-arterial therapy but now evaluated for international shortage of lytic agents.

pubmed.ncbi.nlm.nih.gov/39617030/

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Steven Mathern

@stevenmathern.bsky.social

1 year ago

' #Tenecteplase versus #alteplase for acute stroke within 4·5 h of onset (ATTEST-2): a randomised, parallel group, open-label trial'
#tnkase #tpa #stroke #cva #medsky #neurosky
www.thelancet.com/action/showP...