#bioGUNE_Research | 🧬 New molecular insights in hepatoblastoma
A study led by Malu Martínez-Chantar #CICbioGUNE @brtaeus.bsky.social @ciberisciii.bsky.social @contracancerinv.bsky.social identifies two key proteins (NEDP1 & CAND1) driving hepatoblastoma growth
🔗 www.cicbiogune.es/news/cic-bio...
#bioGUNE_Research |🧠 Astrocytes release extracellular vesicles (EVs) that help neurons resist Alzheimer’s stress by boosting protein synthesis & synaptic health
@achucarro.bsky.social & JuanMa Falcón @ciberisciii.bsky.social #CICbioGUNE @brtaeus.bsky.social
🔗 www.cicbiogune.es/news/astrocy...
#bioGUNE_Research | 🦠 An international team including #CICbioGUNE @brtaeus.bsky.social shows how oral cells reprogram their metabolism in response to Candida albicans
Led by @aizepellon.bsky.social, the study reveals new metabolic pathways with therapeutic potential
🔗 ow.ly/hMwR50Y9eCq
#bioGUNE_Research | 📘 Scientific Annual Review – Issue 8 now available!
Discover State of the Art articles and expert insights from our researchers, highlighting recent advances shaping science at #CICbioGUNE @brtaeus.bsky.social
🔗 www.cicbiogune.es/news-collect...
#bioGUNE_Research | 🧬 An international study led by
Mauro D'Amato #Ikerbasque #CICbioGUNE @brtaeus.bsky.social & #LUMUniversity, published Gut, shows how our genes influence bowel movement frequency, highlighting a surprising link to vitamin B1 (thiamine)
🔗 ow.ly/VeAi50Y01L8
#bioGUNE_Research |🧬 An international study led by
@arkaitzcarracedo.bsky.social Lab #CICbioGUNE @brtaeus.bsky.social, published in @nature.com, shows how polyamines help cells make decisions and protect proteins
@contracancerinv.bsky.social @ciberisciii.bsky.social
🔗 ow.ly/xkuY50XWKRV
#bioGUNE_Research | 🧬 Galectin-9 (gal9) boosts immune activation by organizing dendritic cell synapses, enhancing T cells and tumor control. Published PNAS, with #CICbioGUNE
@brtaeus.bsky.social, it highlights basic immunology’s role in cancer immunotherapy
🔗 ow.ly/x0L250XK87W
#bioGUNE_Research | 🧬 New study shows aggressive prostate cancer reprograms blood vessel-supporting cells (pericytes), driven by macrophage TGF-β, suggesting new ways to restore vascular function
@arkaitzcarracedo.bsky.social @carrerasijc.bsky.social @brtaeus.bsky.social
🔗 ow.ly/uaaF50XGk42
#bioGUNE_Research | 🧬 New study shows PTEN loss remodels prostate tumor tissue, reflecting tumor behavior and helping predict which cancers may become aggressive
🔗 www.cicbiogune.es/news/study-l...
@arkaitzcarracedo.bsky.social #Ikerbasque @brtaeus.bsky.social @ciberisciii.bsky.social
#bioGUNE_Research | The @caixaresearch.bsky.social funds nearly €1M for #GlycoTARGET, led by June Ereño-Orbea #CICbioGUNE #Ikerbasque @brtaeus.bsky.social, to boost cancer immunotherapy with partners from Spain & Portugal
🔗 cicbiogune.es/news/la-caix...
@urv.cat @champalimaudr.bsky.social
#bioGUNE_Research | 🚀 The #ERYSAFETY project kicks off to advance drug safety from the Basque Country
A public–private collaboration funded by #MICIU to develop an innovative model of hemolytic anemia and improve drug safety assessment
🔗 www.cicbiogune.es/news/erysafe...
@ciberisciii.bsky.social
#bioGUNE_Research |🧬 A study led by Millet Lab #CICbioGUNE @brtaeus.bsky.social and published in @ebiomedicine.bsky.social defines age- & sex-specific reference values for 112 lipoprotein parameters via #NMR, improving cardiovascular risk prediction
🔗 ow.ly/Svit50Xqmba
@ciberisciii.bsky.social
#bioGUNE_Research | 🧠 New liver–brain axis!
A collaborative study, led by #CICbioGUNE, shows MASLD impairs memory & sensory processing via hippocampus. Liver-targeted GalNAc-siRNA therapy against CNNM4 reverses these cognitive deficits
🔗 ow.ly/hEWA50XimVF
@ciberisciii.bsky.social
#bioGUNE_Research | 🧬 How do genetic mutations disrupt RNA?
A study led by @monashuniversity.bsky.social, with Mauro D'Amato, decodes the “hidden code” in RNA, paving the way for personalized mRNA therapies and advancing precision medicine
🔗 ow.ly/PN4q50XgO0n
#bioGUNE_Research | 🧬 Could agene predict aggressive prostate cancer?
#CICbioGUNE @brtaeus.bsky.social researchers identify TCF19 as a key driver of tumor growth & metastasis, a potential biomarker & target for personalized therapy
🔗 ow.ly/O5L550X1q51
#bioGUNE_Research |🧬 An international consortium led by #CICbioGUNE identifies CNNM4, a key magnesium transport protein, as a new therapeutic target in cholangiocarcinoma (CCA)
Blocking CNNM4 with GalNAc-siRNA shows therapeutic potential
🔗 ow.ly/VrAP50WXVuA
#bioGUNE_Research | 🧬 A common sucrase-isomaltase variant blunts sugar digestion & blood glucose rise, increasing gut symptoms in IBS. Genetic testing could help personalize diet & treatment
🔗 ow.ly/jRvY50WVFqq
#bioGUNE_Research | 🧬 A study by #CICbioGUNE @brtaeus.bsky.social introduces a new “metabolic clock” to predict biological age, detect early disease & support precision medicine
🔗 ow.ly/zy2O50WT3es
@ciberisciii.bsky.social
#bioGUNE_Research | 🧬 A study by #CICbioGUNE @brtaeus.bsky.social & IIS Biobizkaia reveals that remodeling of the liver ubiquitome and NEDDylome is a hallmark of MASLD
🔗 ow.ly/1Hwm50WAuMG
@ciberisciii.bsky.social @sgiker.bsky.social
#bioGUNE_Research | 🚨 Cover Alert!
A study led by Malu Martínez-Chantar #CICbioGUNE @brtaeus.bsky.social is featured on the cover of #Hepatology @aasldnews.bsky.social
🔗 ow.ly/QoMH50Wt4n5
@caixaresearch.bsky.social
@ciberisciii.bsky.social
#bioGUNE_Research | 🧠An international research team from #CICbioGUNE @brtaeus.bsky.social and @uni.lu develops a brain aging clock that predicts biological age and identifies 453 rejuvenating compounds with potential for neurodegenerative disease therapy
🔗 ow.ly/QCKn50Wt3bu
#bioGUNE_Research |💥 Can our immune system be trained to fight cancer?
A new review led by Dr. Ana Ruiz-Sáenz #CICbioGUNE @brtaeus.bsky.social explores how NK cells and antibody therapies work together via ADCC to destroy tumors
👉 Learn more: www.cicbiogune.es/news/how-do-...
#bioGUNE_Research | 🔬 #CICbioGUNE @brtaeus.bsky.social @ciberisciii.bsky.social deciphers how a key enzyme mutation causes classical homocystinuria, a rare metabolic disease
The study reveals why some patients don't respond to vitamin B6 and suggests new personalized therapies
🔗 ow.ly/u2sm50Wm7bJ
#bioGUNE_Research | 🌍 Our Precision Medicine & Metabolism Lab joined the #NMR Metabolomics Symposium in
Nantes University!
Óscar Millet gave an invited talk & Ricardo Diogo Alves presented his PhD work. Proud to contribute to global progress in #metabolomics!
🔬 #bioGUNE_Research | #CICbioGUNE @brtaeus.bsky.social advances preventive medicine by combining multi-omic data and bioinformatics
The study uncovers early molecular risk signals, showcasing the power of local precision medicine in a Basque cohort
🔗 ow.ly/9IWr50WbmCT
@natureportfolio.nature.com
Curious about the real poster? Meet Irati at pvaconference.wixsite.com/pva2025 in the US!
...and find out how cryo-EM sheds light on complex biological systems thriving in our biosphere
#bioGUNE_Research #brtaeus.bsky.social @cicbiogune.bsky.social
#bioGUNE_Research | 🔬#CICbioGUNE @brtaeus.bsky.social leads a major study on metastatic prostate cancer, revealing how tumor cells "reprogram" normal cells to boost disease progression
📖 Genome Biology @biomedcentral.bsky.social
🔗 ow.ly/nrC150W64WT
@arkaitzcarracedo.bsky.social
#bioGUNE_Research | ✨ Ayer recibimos con mucho gusto a Jesús e Isabel de #CRISContraelCáncer en #CICbioGUNE
@brtaeus.bsky.social
Pudieron conocer de cerca los proyectos en cáncer de mama y próstata que apoyan. ¡Gracias por impulsar la ciencia que salva vidas!
🔗 ow.ly/E2pl50W4Jjf
#bioGUNE_Research | 🧬 New strategies for smart glycan design!
A study, published in #JACS, led by @delbiancom.bsky.social @mpici.bsky.social with Prof. Jesús Jiménez-Barbero's group at #CICbioGUNE @brtaeus.bsky.social reveals how ionic groups control glycan folding
🔗 ow.ly/WLFf50VP1AM
#bioGUNE_Research | 🦟 New insights into Zika virus spread!
A study led by @abrescialab.bsky.social #Ikerbasque #CICbioGUNE @brtaeus.bsky.social reveals how Aedes aegypti salivary proteins modulate the host immune response
🔗 ow.ly/bUoZ50VJnVJ
