#Menin is upregulated in #BladderCancer, driving poor prognosis via TFAP2C/β‑catenin signaling; MEN1 silencing suppressed proliferation, while BAY‑155 inhibited #tumor growth, underscoring menin as a promising therapeutic target for #BLCA.

#OpenAccess: doi.org/10.1016/j.ge...

Black Canyon of the Gunnison National Park #blca #nationalpark
⛔ Park Closure ⛔
Issued: 12/20/2025 12:00 AM EST

Holiday Closures

Black Canyon of the Gunnison's South Rim Visitor Center will be closed for the Christmas holiday on Thursday December 25th. It will also be closed on (1/2)

Black Canyon and Curecanti move to Stage 1 Fire Restrictions Stage 1 Fire Restrictions are in effect. Campfires are prohibited except within designated metal fire grates at campgrounds and picnic areas. Additional restric

Black Canyon of the Gunnison National Park #blca #nationalpark
⚠️ Caution ⚠️
Issued: 9/5/2025 9:46 AM EDT

Stage 1 Fire Restrictions

Stage 1 Fire Restrictions are in effect. Campfires are prohibited except within designated metal fire grates at campgrounds and picnic areas. (1/2)

South Rim of Black Canyon to open South Rim Road - Black Can As of 8/29/2025: South Rim Road and visitor center have reopened; South Rim Campground and some trails remain closed. East Portal remains closed. North Rim is o

Black Canyon of the Gunnison National Park #blca #nationalpark
⛔ Park Closure ⛔
Issued: 8/29/2025 9:39 AM EDT

Park Closures Due to Wildfires

As of 8/29/2025: South Rim Road and visitor center have reopened; South Rim Campground and some trails remain closed. East Portal remains (1/2)

Black Canyon and Curecanti move to Stage 1 Fire Restrictions Stage 1 Fire Restrictions are in effect. Campfires are prohibited except within designated metal fire grates at campgrounds and picnic areas. Additional restric

Black Canyon of the Gunnison National Park #blca #nationalpark
⚠️ Caution ⚠️
Issued: 9/5/2025 9:46 AM EDT

Stage 1 Fire Restrictions

Stage 1 Fire Restrictions are in effect. Campfires are prohibited except within designated metal fire grates at campgrounds and picnic areas. (1/2)

Black Canyon and Curecanti move to Stage 1 Fire Restrictions Stage 1 fire restrictions are in effect. Campfires are prohibited except within designated metal fire grates at campgrounds and picnic areas. Additional restric

Black Canyon of the Gunnison National Park #blca #nationalpark
⚠️ Caution ⚠️
Issued: 9/5/2025 9:38 AM EDT

Stage 1 Fire Restrictions

Stage 1 fire restrictions are in effect. Campfires are prohibited except within designated metal fire grates at campgrounds and picnic areas. (1/2)

South Rim of Black Canyon to open South Rim Road - Black Can As of 8/29/2025: South Rim Road and visitor center have reopened; South Rim Campground and some trails remain closed. East Portal remains closed. North Rim is o

Black Canyon of the Gunnison National Park #blca #nationalpark
⛔ Park Closure ⛔
Issued: 8/29/2025 9:39 AM EDT

Park Closures Due to Wildfires

As of 8/29/2025: South Rim Road and visitor center have reopened; South Rim Campground and some trails remain closed. East Portal remains (1/2)

South Rim of Black Canyon to open - Black Canyon Of The Gunn South Rim is partially open for day use as of 8/18/2025. North Rim is open. East Portal remains closed. Do not enter closed or burned areas until further notice

Black Canyon of the Gunnison National Park #blca #nationalpark
⛔ Park Closure ⛔
Issued: 8/27/2025 3:31 PM EDT

Park Closures Due to Wildfires

South Rim is partially open for day use as of 8/18/2025. North Rim is open. East Portal remains closed. Do not enter closed or burned areas (1/2)

South Rim of Black Canyon to open - Black Canyon Of The Gunn South Rim to partially open 8/18/2025. North Rim opened 7/30/2025. East Portal remains closed. Do not enter closed or burned areas until further notice.

Black Canyon of the Gunnison National Park #blca #nationalpark
⛔ Park Closure ⛔
Issued: 8/14/2025 4:08 PM EDT

Park Closures Due to Wildfires

South Rim to partially open 8/18/2025. North Rim opened 7/30/2025. East Portal remains closed. Do not enter closed or burned areas until (1/2)

South Rim of Black Canyon to open - Black Canyon Of The Gunn South Rim to partially open 8/18/2025. North Rim opened on 7/30/2025. East Portal remains closed. Do not enter closed areas until further notice.

Black Canyon of the Gunnison National Park #blca #nationalpark
⛔ Park Closure ⛔
Issued: 8/14/2025 1:57 PM EDT

Park Closures Due to Wildfires

South Rim to partially open 8/18/2025. North Rim opened on 7/30/2025. East Portal remains closed. Do not enter closed areas until further (1/2)

Black Canyon and Curecanti move to Stage 2 Fire Restrictions The park is in Stage 2 fire restrictions due to high fire danger. The following are prohibited: campfires including charcoal, smoking except inside a vehicle, a

Black Canyon of the Gunnison National Park #blca #nationalpark
⚠️ Caution ⚠️
Issued: 8/14/2025 1:50 PM EDT

Stage 2 Fire Restrictions

The park is in Stage 2 fire restrictions due to high fire danger. The following are prohibited: campfires including charcoal, smoking except inside a (1/2)

Black Canyon of the Gunnison National Park #blca #nationalpark
⛔ Park Closure ⛔
Issued: 8/14/2025 12:54 PM EDT

Wildfire Closures and Reservation Cancellations

South Rim and East Portal campgrounds are closed and reservations are cancelled; all South Rim inner canyon wilderness (1/2)

South Rim is a type of Incident | InciWeb The is located in the state of . It is part of incident unit(s): Black Canyon of the Gunnison National Park  102 Elk Creek Gunnison Colorado 81230  Gunnison,  C

Black Canyon of the Gunnison National Park #blca #nationalpark
⛔ Park Closure ⛔
Issued: 8/8/2025 11:55 AM EDT

Park Closures Due to Wildfires

South Rim and East Portal are closed; the North Rim opened on 7/30/2025. Do not enter closed areas until further notice. Updates on the South (1/2)

South Rim is a type of Incident | InciWeb The is located in the state of . It is part of incident unit(s): Black Canyon of the Gunnison National Park  102 Elk Creek Gunnison Colorado 81230  Gunnison,  C

Black Canyon of the Gunnison National Park #blca #nationalpark
⛔ Park Closure ⛔
Issued: 7/29/2025 1:54 PM EDT

Park Closures Due to Wildfires

South Rim and East Portal are closed; North Rim to open 7/30/2025. Do not enter closed areas until further notice. Updates on the South Rim (1/2)

Black Canyon of the Gunnison National Park #blca #nationalpark
⛔ Park Closure ⛔
Issued: 7/29/2025 1:10 PM EDT

Wildfire Closures and Reservation Cancellations

South Rim and East Portal campgrounds are closed and reservations are cancelled; all South Rim inner canyon wilderness (1/2)

South Rim is a type of Incident | InciWeb The is located in the state of . It is part of incident unit(s): Black Canyon of the Gunnison National Park  102 Elk Creek Gunnison Colorado 81230  Gunnison,  C

Black Canyon of the Gunnison National Park #blca #nationalpark
⛔ Park Closure ⛔
Issued: 7/29/2025 1:04 PM EDT

Park Closures Due to Wildfires

The South Rim and East Portal are closed; North Rim will open 7/30/2025. Do not enter closed areas until further notice. Updates on the South (1/2)

South Rim is a type of Incident | InciWeb The is located in the state of . It is part of incident unit(s): Black Canyon of the Gunnison National Park  102 Elk Creek Gunnison Colorado 81230  Gunnison,  C

Black Canyon of the Gunnison National Park #blca #nationalpark
⛔ Park Closure ⛔
Issued: 7/29/2025 12:56 PM EDT

Park Closures Due to Wildfires

The South Rim and East Portal are closed; North Rim will open 7/30/2025. Do not enter closed areas until further notice. Updates on the (1/2)

Black Canyon of the Gunnison National Park #blca #nationalpark
⛔ Park Closure ⛔
Issued: 7/18/2025 11:37 AM EDT

Wildfire Closures and Reservation Cancellations

Due to wildfire damage, the following are in effect until further notice: all campgrounds are closed and reservations are (1/2)

South Rim is a type of Incident | InciWeb The is located in the state of . It is part of incident unit(s): Black Canyon of the Gunnison National Park  102 Elk Creek Gunnison Colorado 81230  Gunnison,  C

Black Canyon of the Gunnison National Park #blca #nationalpark
⛔ Park Closure ⛔
Issued: 7/14/2025 6:32 PM EDT

Park Closed Due to Wildfires

Both the North Rim and South Rim are closed; East Portal is not accessible. Do not enter the park until further notice. Updates on the South (1/2)

Laws & Regulations - Black Canyon Of The Gunnison National P Both the North Rim and South Rim are closed; East Portal is not accessible. Do not enter the park until further notice. Updates on the South Rim Fire will be pr

Black Canyon of the Gunnison National Park #blca #nationalpark
⛔ Park Closure ⛔
Issued: 7/13/2025 3:52 PM EDT

Park Closed Due to Wildfires

Both the North Rim and South Rim are closed; East Portal is not accessible. Do not enter the park until further notice. Updates on the South (1/2)

South Rim is a type of Incident | InciWeb The is located in the state of . It is part of incident unit(s): Black Canyon of the Gunnison National Park  102 Elk Creek Gunnison Colorado 81230  Gunnison,  C

Black Canyon of the Gunnison National Park #blca #nationalpark
⛔ Park Closure ⛔
Issued: 7/13/2025 3:38 PM EDT

Park Closed Due to Wildfires

Both the North Rim and South Rim are closed; East Portal is not accessible. Do not enter the park until further notice. Updates on the South (1/2)

Life at #BLCA, Black Canyon of the Gunnison National Park, 2023. Threatened now by fire.

Black Canyon of the Gunnison National Park #blca #nationalpark
⚡ Danger ⚡
Issued: 7/11/2025 6:09 PM EDT

Park Closed Due to Wildfires

Both the North Rim and South Rim are closed; East Portal is not accessible. Do not enter the park until further notice. Updates on the South Rim Fire (1/2)

Black Canyon of the Gunnison National Park #blca #nationalpark
⚡ Danger ⚡
Issued: 7/10/2025 3:18 PM EDT

Park Closed Due to Wildfires

Lightning-caused wildfires are burning on both rims of Black Canyon. The park is currently closed and all visitors and staff are being evacuated. Do (1/2)

Roadwork at Black Canyon - Black Canyon Of The Gunnison Nati On various dates during July 2025, vehicle access to the South Rim Campground will be limited due to roadwork. Click the link below for additional details.

Black Canyon of the Gunnison National Park #blca #nationalpark
⛔ Park Closure ⛔
Issued: 7/3/2025 5:22 PM EDT

South Rim Campground access affected during roadwork

On various dates during July 2025, vehicle access to the South Rim Campground will be limited due to roadwork. Click the (1/2)

Black Canyon of the Gunnison National Park #blca #nationalpark
⛔ Park Closure ⛔
Issued: 7/3/2025 2:44 PM EDT

East Portal Campground closure during roadwork

East Portal Campground will be closed July 24, 2025, due to roadwork. The campground is first-come first-served; no (1/2)

Black Canyon of the Gunnison National Park #blca #nationalpark
⛔ Park Closure ⛔
Issued: 7/3/2025 12:09 PM EDT

East Portal Campground closure during roadwork

East Portal Campground will be closed July 22-23, 2025 due to roadwork. The campground is first-come first-served; no (1/2)

Black Canyon of the Gunnison National Park #blca #nationalpark
⛔ Park Closure ⛔
Issued: 7/1/2025 4:30 PM EDT

East Portal Campground closure during roadwork

The East Portal Campground will be closed on July 22-23, 2025 due to roadwork. The campground is first-come first-served; no (1/2)

Black Canyon of the Gunnison National Park #blca #nationalpark
⛔ Park Closure ⛔
Issued: 6/27/2025 10:13 AM EDT

South Rim Campground closure during roadwork

Roadwork will close portions of South Rim Campground as soon as July 7. Reservations for campsites that are inaccessible (1/2)

Camping - Black Canyon Of The Gunnison National Park (U.S. N Black Canyon's operations are now cashless. South Rim Campground is by reservation only via Recreation.gov. East Portal & North Rim campgrounds accept payment f

Black Canyon of the Gunnison National Park #blca #nationalpark
ℹ️ Information ℹ️
Issued: 5/28/2025 5:25 PM EDT

Cashless Operations

Black Canyon's operations are now cashless. South Rim Campground is by reservation only via Recreation.gov. East Portal & North Rim campgrounds accept (1/2)