#Menin is upregulated in #BladderCancer, driving poor prognosis via TFAP2C/β‑catenin signaling; MEN1 silencing suppressed proliferation, while BAY‑155 inhibited #tumor growth, underscoring menin as a promising therapeutic target for #BLCA.
#OpenAccess: doi.org/10.1016/j.ge...
Black Canyon of the Gunnison National Park #blca #nationalpark
⛔ Park Closure ⛔
Issued: 12/20/2025 12:00 AM EST
Holiday Closures
Black Canyon of the Gunnison's South Rim Visitor Center will be closed for the Christmas holiday on Thursday December 25th. It will also be closed on (1/2)
Black Canyon of the Gunnison National Park #blca #nationalpark
⚠️ Caution ⚠️
Issued: 9/5/2025 9:46 AM EDT
Stage 1 Fire Restrictions
Stage 1 Fire Restrictions are in effect. Campfires are prohibited except within designated metal fire grates at campgrounds and picnic areas. (1/2)
Black Canyon of the Gunnison National Park #blca #nationalpark
⛔ Park Closure ⛔
Issued: 8/29/2025 9:39 AM EDT
Park Closures Due to Wildfires
As of 8/29/2025: South Rim Road and visitor center have reopened; South Rim Campground and some trails remain closed. East Portal remains (1/2)
Black Canyon of the Gunnison National Park #blca #nationalpark
⚠️ Caution ⚠️
Issued: 9/5/2025 9:46 AM EDT
Stage 1 Fire Restrictions
Stage 1 Fire Restrictions are in effect. Campfires are prohibited except within designated metal fire grates at campgrounds and picnic areas. (1/2)
Black Canyon of the Gunnison National Park #blca #nationalpark
⚠️ Caution ⚠️
Issued: 9/5/2025 9:38 AM EDT
Stage 1 Fire Restrictions
Stage 1 fire restrictions are in effect. Campfires are prohibited except within designated metal fire grates at campgrounds and picnic areas. (1/2)
Black Canyon of the Gunnison National Park #blca #nationalpark
⛔ Park Closure ⛔
Issued: 8/29/2025 9:39 AM EDT
Park Closures Due to Wildfires
As of 8/29/2025: South Rim Road and visitor center have reopened; South Rim Campground and some trails remain closed. East Portal remains (1/2)
Black Canyon of the Gunnison National Park #blca #nationalpark
⛔ Park Closure ⛔
Issued: 8/27/2025 3:31 PM EDT
Park Closures Due to Wildfires
South Rim is partially open for day use as of 8/18/2025. North Rim is open. East Portal remains closed. Do not enter closed or burned areas (1/2)
Black Canyon of the Gunnison National Park #blca #nationalpark
⛔ Park Closure ⛔
Issued: 8/14/2025 4:08 PM EDT
Park Closures Due to Wildfires
South Rim to partially open 8/18/2025. North Rim opened 7/30/2025. East Portal remains closed. Do not enter closed or burned areas until (1/2)
Black Canyon of the Gunnison National Park #blca #nationalpark
⛔ Park Closure ⛔
Issued: 8/14/2025 1:57 PM EDT
Park Closures Due to Wildfires
South Rim to partially open 8/18/2025. North Rim opened on 7/30/2025. East Portal remains closed. Do not enter closed areas until further (1/2)
Black Canyon of the Gunnison National Park #blca #nationalpark
⚠️ Caution ⚠️
Issued: 8/14/2025 1:50 PM EDT
Stage 2 Fire Restrictions
The park is in Stage 2 fire restrictions due to high fire danger. The following are prohibited: campfires including charcoal, smoking except inside a (1/2)
Black Canyon of the Gunnison National Park #blca #nationalpark
⛔ Park Closure ⛔
Issued: 8/14/2025 12:54 PM EDT
Wildfire Closures and Reservation Cancellations
South Rim and East Portal campgrounds are closed and reservations are cancelled; all South Rim inner canyon wilderness (1/2)
Black Canyon of the Gunnison National Park #blca #nationalpark
⛔ Park Closure ⛔
Issued: 8/8/2025 11:55 AM EDT
Park Closures Due to Wildfires
South Rim and East Portal are closed; the North Rim opened on 7/30/2025. Do not enter closed areas until further notice. Updates on the South (1/2)
Black Canyon of the Gunnison National Park #blca #nationalpark
⛔ Park Closure ⛔
Issued: 7/29/2025 1:54 PM EDT
Park Closures Due to Wildfires
South Rim and East Portal are closed; North Rim to open 7/30/2025. Do not enter closed areas until further notice. Updates on the South Rim (1/2)
Black Canyon of the Gunnison National Park #blca #nationalpark
⛔ Park Closure ⛔
Issued: 7/29/2025 1:10 PM EDT
Wildfire Closures and Reservation Cancellations
South Rim and East Portal campgrounds are closed and reservations are cancelled; all South Rim inner canyon wilderness (1/2)
Black Canyon of the Gunnison National Park #blca #nationalpark
⛔ Park Closure ⛔
Issued: 7/29/2025 1:04 PM EDT
Park Closures Due to Wildfires
The South Rim and East Portal are closed; North Rim will open 7/30/2025. Do not enter closed areas until further notice. Updates on the South (1/2)
Black Canyon of the Gunnison National Park #blca #nationalpark
⛔ Park Closure ⛔
Issued: 7/29/2025 12:56 PM EDT
Park Closures Due to Wildfires
The South Rim and East Portal are closed; North Rim will open 7/30/2025. Do not enter closed areas until further notice. Updates on the (1/2)
Black Canyon of the Gunnison National Park #blca #nationalpark
⛔ Park Closure ⛔
Issued: 7/18/2025 11:37 AM EDT
Wildfire Closures and Reservation Cancellations
Due to wildfire damage, the following are in effect until further notice: all campgrounds are closed and reservations are (1/2)
Black Canyon of the Gunnison National Park #blca #nationalpark
⛔ Park Closure ⛔
Issued: 7/14/2025 6:32 PM EDT
Park Closed Due to Wildfires
Both the North Rim and South Rim are closed; East Portal is not accessible. Do not enter the park until further notice. Updates on the South (1/2)
Black Canyon of the Gunnison National Park #blca #nationalpark
⛔ Park Closure ⛔
Issued: 7/13/2025 3:52 PM EDT
Park Closed Due to Wildfires
Both the North Rim and South Rim are closed; East Portal is not accessible. Do not enter the park until further notice. Updates on the South (1/2)
Black Canyon of the Gunnison National Park #blca #nationalpark
⛔ Park Closure ⛔
Issued: 7/13/2025 3:38 PM EDT
Park Closed Due to Wildfires
Both the North Rim and South Rim are closed; East Portal is not accessible. Do not enter the park until further notice. Updates on the South (1/2)
Black Canyon of the Gunnison National Park #blca #nationalpark
⚡ Danger ⚡
Issued: 7/11/2025 6:09 PM EDT
Park Closed Due to Wildfires
Both the North Rim and South Rim are closed; East Portal is not accessible. Do not enter the park until further notice. Updates on the South Rim Fire (1/2)
Black Canyon of the Gunnison National Park #blca #nationalpark
⚡ Danger ⚡
Issued: 7/10/2025 3:18 PM EDT
Park Closed Due to Wildfires
Lightning-caused wildfires are burning on both rims of Black Canyon. The park is currently closed and all visitors and staff are being evacuated. Do (1/2)
Black Canyon of the Gunnison National Park #blca #nationalpark
⛔ Park Closure ⛔
Issued: 7/3/2025 5:22 PM EDT
South Rim Campground access affected during roadwork
On various dates during July 2025, vehicle access to the South Rim Campground will be limited due to roadwork. Click the (1/2)
Black Canyon of the Gunnison National Park #blca #nationalpark
⛔ Park Closure ⛔
Issued: 7/3/2025 2:44 PM EDT
East Portal Campground closure during roadwork
East Portal Campground will be closed July 24, 2025, due to roadwork. The campground is first-come first-served; no (1/2)
Black Canyon of the Gunnison National Park #blca #nationalpark
⛔ Park Closure ⛔
Issued: 7/3/2025 12:09 PM EDT
East Portal Campground closure during roadwork
East Portal Campground will be closed July 22-23, 2025 due to roadwork. The campground is first-come first-served; no (1/2)
Black Canyon of the Gunnison National Park #blca #nationalpark
⛔ Park Closure ⛔
Issued: 7/1/2025 4:30 PM EDT
East Portal Campground closure during roadwork
The East Portal Campground will be closed on July 22-23, 2025 due to roadwork. The campground is first-come first-served; no (1/2)
Black Canyon of the Gunnison National Park #blca #nationalpark
⛔ Park Closure ⛔
Issued: 6/27/2025 10:13 AM EDT
South Rim Campground closure during roadwork
Roadwork will close portions of South Rim Campground as soon as July 7. Reservations for campsites that are inaccessible (1/2)
Black Canyon of the Gunnison National Park #blca #nationalpark
ℹ️ Information ℹ️
Issued: 5/28/2025 5:25 PM EDT
Cashless Operations
Black Canyon's operations are now cashless. South Rim Campground is by reservation only via Recreation.gov. East Portal & North Rim campgrounds accept (1/2)