CRISPR-Cas9-mediated elimination of plasmid-borne #carbapenemase genes restores ertapenem susceptibility in clinical #Klebsiella pneumoniae isolates

www.sciencedirect.com/science/arti... #OpenAccess #MicroSky

Multidrug-resistant bacteria detected in Chilean wastewater for the first time A team of Chilean researchers has identified, for the first time in the country, the presence of KPC-type carbapenemase-producing bacteria in wastewater samples from the Greater Concepción…

#Multidrug-resistant #bacteria detected in #Chilean #wastewater for the first time ...

| #Chile | #carbapenemase | #antibiotics | #antibioticresistance | Via @sciencex.bsky.social

🦠 Tricia Lee takes us through the largest genomic investigation of OXA-181 in Australia to date. Discover how long-read sequencing characterised plasmid-mediated OXA-181 spread following a hospital outbreak. #MicroSeq2025 #bacteria #carbapenemase #antimicrobialresistance

Cross-border spread of a mosaic resistance (OXA-48) and virulence (aerobactin) plasmid in Klebsiella pneumoniae: a European Antimicrobial Resistance Genes Surveillance Network investigation, Europe, F... An investigation of the European Antimicrobial Resistance Genes Surveillance Network (EURGen-Net) detected the same mosaic IncHI1B(pNDM-MAR) resistance (OXA-48) and virulence (aerobactin) plasmid in 4...

www.eurosurveillance.org/content/10.2...
#ECDC #RIVM #plasmids #genomicsurveillance #nanopore #virulence #carbapenemase

Starting the third day with #rapidAST. What’s new trying to get faster AND better? Julia Rogers presents a new lateral flow test that can detect the presence of an important betalactamase: KP2 #carbapenemase

Test like this would be incredibly helpful in low-resource settings!

On Monday we are releasing a new #Communicable podcast episode - the 2nd round of the Nightmare Series. @angelahuttner.bsky.social & Thomas sit down w/ David Patterson & Souha Kanj to discuss clinical challenges of dealing w/ #carbapenemase producers. Swipe for preview!

#IDSky #MedSky #AMR