Macromolecular interactions dictate Polycomb-mediated epigenetic repression The dynamic regulation of epigenetic states relies on complex macromolecular interactions. PRC2, the methyltransferase complex responsible for depositing H3K27me3, interacts with distinct accessory pr...

Beautiful and important work by the group of @yichenglong.bsky.social at Weill Cornell on the molecular determinants that direct epigenetic repression by Polycomb complexes. www.biorxiv.org/content/10.1... #epigenetics #stemcells #cardiogenesis #polycomb

#RandomHashtagOfTheDay for Monday, January 27 is: #cardiogenesis