REVEAL study: Axatilimab + ruxolitinib achieved 69% ORR in R/R #cGvHD. π©Ί
60% of patients reported β₯1 Grade 3 TEAE.
20.5% experienced Grade 4.
Findings from #Tandem26 via @astct.bsky.social @cibmtr.bsky.social
Read the review: https://bit.ly/4cyLJ9o
#Hematology #GvHD #MedicalNews
Combining post-transplantation cyclophosphamide with sirolimus and cyclosporine appears to reduce the incidence of #cGVHD compared with sirolimus, cyclosporine, and MMF. Published in @ascopost.bsky.social Journal of Clinical Oncology.
https://bit.ly/48VJZnn
#GVHD
Rezurock 200 mg Tablet contains Belumosudil, prescribed for chronic graft-versus-host disease (cGVHD) in patients 12 years and older who did not respond to prior treatments.
#rezurock #belumosudil #cgvhd #belumosudil200 #rezurock200
www.drugsgeneral.com/rezurock-200...
Heading to #WTC2025? See Joe Douglas presenting in Abstract Session RF01.1 β Fundamentals of Transplantation Science. ποΈ SUN 8/3 π 7-8am PDT π Room 12
Use of BMT CTN 1202 Samples to Develop an Algorithm for Prediction & Diagnosis of cGvHD for Peripheral Blood HCT Recipients.
π LINKS π
#cGvHD #BMT
#OrcaBio #allogeneiccelltherapy #OrcaT #Tcelltherapy #investigationalallogeneicTcellimmunotherapy #PrecisionTtrial #acutemyeloidleukaemia #acutelymphoblasticleukaemia #highriskmyelodysplasticsyndrome #mixedphenotypeacuteleukaemia #alloHSCT #cGvHD #alloHSCT
pharmatimes.com/news/orca-bi...
Fred Hutch at #Tandem25: Dr. Masumi Ueda Oshima to present results of a novel drug regimen that shows great promise in preventing #cGVHD after transplant in people who received nonmyeloablative or reduced-intensity conditioning to treat a blood cancer. bit.ly/411oqO2
Abbisko's Pimicotinib Shows Promise in Treating Chronic Graft-versus-Host Disease at ASH 2024 #China #Shanghai #Abbisko #Pimicotinib #cGvHD
A somewhat obscure chronic illness #cGvHD or GvHD chronic Graft vs Host Disorder - a complication of bone marrow/stem cell transplant. Thanks!