Transcriptomic analysis identifies the neuropeptide cortistatin (CORT) as an inhibitor of temozolomide (TMZ) resistance by suppressing the NF-κB-MGMT signaling axis in human glioma

This study reveals that #cortistatin inhibits the activation of the NF-κB pathway in #glioma cells, thereby inhibiting MGMT expression, and interference with its expression could be a promising strategy for overcoming #Temozolomide resistance in glioma. #medsky

#OpenAccess: buff.ly/NTUa3XR