The Impact of Surgical Strategy and Rifampin on Treatment Outcome in Cutibacterium Periprosthetic Joint Infections In this retrospective study, we observed no significant benefit of using rifampin to avoid relapses or new infections but a benefit when the prosthesis was

#cutibacterium #PJI no role for rifampin academic.oup.com/cid/article/...

#cutibacterium #PJI treatment removal of hardware and penicillin based on susceptibilites. Alternatives cefazolin or ceftriaxone. Initial 2 weeks of iv abx f/b oral abx to complete 6 wk course. oral options 1st gen cephalosporin, alternative clinda, linezolid

https://www.jshoulderelbow.org/article/S1058-2746(20)30957-5/fulltext

#cutibacterium #PJI t.co/GRNkE2nygP

Culturing multiple sites from operative wound helps distinguish contamination from infection by common skin flora as Staph epi & #Cutibacterium acnes
Inoculating joint fluid into blood culture bottles is useful if the bottles are incubated up to 2wks

median time for #cutibacterium acnes infection of a shoulder prothesis is 15 months. Pain & stiffness, without fever or leukocytosis, is most common presentation. Patients often have normal ESR & CRP & fewer inflammatory cells than seen with infection due to other organisms

when concern about #cutibacterium acnes #PJI: ask to obtain 3-5 pieces of tissue from the infected site &request the lab hold aerobic and anaerobic cultures for 14 days

#Cutibacterium acnes most common cause of shoulder prosthetic joint infection and infects other prosthetic joints as well. Routine wound cultures are incubated by most labs for only 3 days, whereas #Cutibacterium acnes requires up to 2weeks of anaerobic incubation to grow

Plasma cell infiltration could be a marker of chronic bone and joint infection #BJI due to #Cutibacterium acnes: a series of 21 patients managed @CHUdeLyon @CrioacLyon just published as an #OpenAccess paper in #JBJI ➡️

jbji.net/v05p0205.htm