Tremelimumab and durvalumab as neoadjuvant or non-operative management strategy of patients with microsatellite instability-high resectable gastric or gastroesophageal junction adenocarcinoma: the INF... In resectable gastric/gastroesophageal junction adenocarcinoma, microsatellite instability-high (MSI-H) confers improved survival, but limited benefit…

Exciting #GIonc INFINITY ♾ #Ph2 trial

Neoadjuvant #IO in #stcsm #esocsm using #treme + #durva ~60% pCR

12m 🚫🔪#survival ~ 64%.

#Ph3 data needed, but organ preservation possible!

🔗: sciencedirect.com/science/arti...