A phase 2a open-label clinical trial to determine the effect of famciclovir on EBV activity as measured by EBV shedding in the saliva of patients with multiple sclerosis - PubMed No significant effect of famciclovir on EBV shedding was seen in this small pilot study. Given the low numbers, a small effect of famciclovir cannot be excluded. Salivary EBV shedding in this natalizu...

There is some data that the acyclovir prodrug #valacyclovir (which I take to halt ebv reactivations) is more effective than #guanasineanalogue antivirals.

Better results may come in a trial of late onset #MS or secondary MSers. Viral control ability depleted. 1/2

pubmed.ncbi.nlm.nih.gov/38131621/