#Medsky🧪 #IDsky #immunosky #publichealth #Interferonopathies drive #autoimmunity but can also impair host responses to pathogens, including #viralinfections. Human gain of function (GOF) mutations in STAT1—a critical signaling molecule downstream of interferons (IFNs)

Excessive type I IFN, perhaps counterintuitively, appears to underlie a greater number of #autoinflammatory and/or autoimmune conditions known as type I #interferonopathies, whose study has revealed multiple molecular programs involved in the induction of type I IFN signaling.

🔬 Meet the Researchers Behind IMMERGE! 🔬

This week: @angelopilotti.bsky.social & Dr. Pierre from @cnrs.fr!
Angelo will study the functional impact of EIF2AK mutants in dendritic cells & interferonopathies🧬👨‍🔬

Stay tuned for more IMMERGE scientists! 🚀

#IMMERGE #MSCA #IEI #DCs #Interferonopathies