#lilrb4

Fc gamma receptors promote antibody-induced LILRB4 internalization and immune regulation of monocytic AML Statement of Significance: Receptor internalization mediated by the LILRB4 neutralizing antibody h128-3 is in part dependent on the IgG1-Fc interaction wit

Antibody Therapeutics(IF=4.5, Oxford University Press)
🚀🚀Fc gamma receptors promote antibody-induced LILRB4 internalization and immune regulation of monocytic AML
academic.oup.com/abt/article/...
#FcGammaReceptor #LILRB4 #AML

Cancer Hijacks Immune System via Hormone SCG2, Study Finds

Scientists showed secretogranin 2 (SCG2) binds LILRB4 on myeloid cells, triggering STAT3; blocking LILRB4 or deleting SCG2 slowed tumor growth in mice (Nature Immunology). getnews.me/cancer-hijacks-immune-sy... #scg2 #lilrb4