Beyond the loss of beta cells: a quantitative analysis of islet architecture in adults with and without type 1 diabetes - Diabetologia Aims/hypothesis The organisation and cellular architecture of islets of Langerhans are critical to the physiological regulation of hormone secretion but it is debated whether human islets adhere to th...

Using a fusion of #mathematics and #spatial_biology, a study employing quantitative tools (including the #Earth_Movers_Distance metric) tests the existence of a #mantle_core_structure in #human_islets in #T1D link.springer.com/article/10.1... 🔓