LncRNA MEG3 Inhibits the Epithelial-mesenchymal Transition of Bladder Cancer Cells through the Snail/E-cadherin Axis - Current Medical Science Objective This study aimed to investigate the role of the long noncoding RNA (lncRNA) maternally expressed gene 3 (MEG3) in the epithelial-mesenchymal transition (EMT) of bladder cancer cells and the…

This study reveals that #lncRNA #Maternally expressed gene 3 (MEG3) suppresses #EpithelialMesenchymalTransition by modulating #Ecadherin via Snail/#MAPK regulation, positioning MEG3 as a potential #therapeutic target for #BladderCancer. #medsky

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These genes can have the opposite effects depending on which parent they came from New approach finds ‘parent-of-origin’ effects in more than a dozen genes — without the need for parental data.

Some #genes exhibit parent-of-origin effects, behaving differently depending on whether they’re inherited #maternally or #paternally.

A novel approach has identified such effects in over a dozen genes, all without the need for parental #genotype data

www.nature.com/articles/d41...