#Myostatin promotes proliferation of #bovine #muscle satellite #cells through activating TRPC4/Ca2+/calcineurin/NFATc3 pathway
🌈https://doi.org/10.1016/j.jia.2024.04.020
#AnimalScience

Researchers of Southwest University in Chongqing, China, have successfully used CRISPR/Cas9 gene-editing to make grass carp grow faster and develop more muscle by switching off a natural “brake” gene, mstnb. Learn more:https://ow.ly/hGRb50XWvBj
#CRISPR/Cas9 #GenomeEditing #GrassCarp #Myostatin

Myostatin inhibitors have received a lot of attention in the muscle space.

They work great in mice, but there's another strategy with far greater potential in humans.

I break down the #Science in this thread. 🧪💊🧪

#myostatin #muscle #healthspan #longevity

Patients with #COPD who suffer from #sarcopenia, show higher levels of a protein linked to muscle growth regulation, #myostatin

This may explain the high prevalence in these patients

#sarcopenia #pneumologia @hospitaldelmar.bsky.social @ciberisciii.bsky.social

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