Another #NACCT16 in the books! See everyone next year in Vancouver.

#NACCT16 Special guest for the tweeter!

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#NACCT16 Tweeeeeeeeee!

Can Poison Control Centers be automated? #NACCT16 Mobile app has one yr experience. "Not appropriate if symptomatic

Poison Center Calls: Factors associated with call penetrance #NACCT16 @AAPCC

Systemic loxoscelism (brown recluse spider bite) requiring ECMO in a 9 yo boy #NACCT16 #FOAMed #FOAMtox

Myocardial infarction in 16 yo with MJ inhalation, #synthetic screening negative #NACCT16 #FOAMed #FOAMtox

KRATOM overdose clinical effects in 10 ED patients #NACCT16 #FOAMed #KratomSavesLives #FOAMtox

PRN >> Maintenence crofab dosing based on 8 yr study at the U.S. snake bite Mecca #NACCT16 congrats @mbspyres

BREAKING: RCT analatro antivenom vs PLACEBO for systemic latrodectism (black widow) to prevent Rx failures #NACCT16

Case 3: Prisoner ingested animal, BIBA with n/v, bradycardia, elevated dig level. Due to bufo toad ingestion! #NACCT16

Case 2: 22 M forages plant, makes soup, then drives to ED with n/v hypoTN, bradycardia o/w normal ECG. Plant ID.... Death Camas #NACCT16

Case 1: 21 M eats powder, has N/V/D long QT, 🔼 lactate, has radio opaq mat in abd xray. C/B Torsades, death. Caused by.... Arsenic! #NACCT16

Up next is the CPC #NACCT16

"Abuse deterrent formulations are necessary but insufficient to prevent abuse", and probably do not prevent addiction #NACCT16 @LNelsonMD

Between 5-23% of people taking opioids as directed for a year develop addiction #NACCT16, as per @LNelsonMD

Indications for Praxbind 1) emergency surgery, or 2) life threatening bleeding #NACCT16 REVERSE-AD final results yet to be published

"In the real world, bad things happen more often than in clinical trials" -Professor Bauer #NACCT16

When NOT to use DOACs to treat VTE #NACCT16

DOACs are all potent P-glycoprotein inhibitors #nacct16 #FOAMed #FOAMtox

Spinal tap is contraindicated if the patient is taking a DOAC #nacct16 #FOAMed

NOAC terminology is dated! New name: Direct Oral Anticoagulants (DOACs) #nacct16 #noac #DOAc

"MAb antidotes are safer than the molecules they intend to reverse, but they can still cause adverse events" #nacct16 as per @toxicologist12

mAb Chemotherapy infusion reactions are expected events, due to cytokine release, and are less severe with subsequent doses of drug #nacct16

If you want to study mAbs, your IRB will expect a detailed plan about how you manage adverse reactions to the drug #nacct16

Monoclonal antibody naming conventions #NACCT16 #FOAMed #FOAMtox

Monoclonal Abs are one of the fastest growing drug categories approved by FDA in recent years , per @toxicologist12 #NACCT16

Up next at #nacct16 is @toxicologist12 with a skull and crossbones bowtie talking about mAbs in Toxicology

Suggamedex chelates Roc for reversal of neuromuscular blockade. Indications include "cannot intubate, cannot ventilate" situation #nacct16

"People should not underestimate how important exclusivity is to a drug company" - @LNelsonMD #nacct16