CTCF Binding Site Mutations: Linking Topologically Associated Domains Dysregulation to Cutaneous Squamous Cell Carcinoma Progression Background Cutaneous squamous cell carcinoma (cSCC) is the most common lethal malignancy with metastatic potential. The high mutational burden in cSCC has made it difficult to understand the significa...

🚨 New preprint!
CTCF Binding Site Mutations: Linking TAD Dysregulation to cSCC Progression
We show how mutations at CTCF sites drive metastasis in skin cancer.
🧬📊 dx.doi.org/10.21203/rs....

#Genomics #CTCF #3Dgenome #cSCC #Bioinformatics #Cancer #nswheath