Cancer cells no longer respond to the rules and signals of the body, which upsets its balance.
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“Tumor suppressor BAP1 suppresses disulfidptosis through the regulation of SLC7A11 and NADPH levels”
🔵 Interesting research led by Qiuran Xuwas featured in #Oncogenesis.
▶️ Read the full open access article here: www.nature.com/articles/s41...
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“Teriflunomide modulates the PD-1/PD-L1 axis and enhances antitumor immunity in colorectal cancer”
🔵 Hwan-Suck Chung‘s latest research is now available to read in #Oncogenesis.
▶️ Read the full open access article here: www.nature.com/articles/s41...
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“TFCP2L1 drives stemness and enhances their resistance to Sorafenib treatment by modulating the NANOG/STAT3 pathway in hepatocellular carcinoma”
🔵 Interesting research led by Changchang Jia was featured in #Oncogenesis.
▶️ Read the full open access article here: www.nature.com/articles/s41...
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“Inhibition of ZBTB7B-mediated ADPGK transcription by NEDD4 impedes glycolysis and progression of lung adenocarcinoma”
🔵 Tao Wang‘s latest research is now available to read in #Oncogenesis.
▶️ Read the full open access article here: www.nature.com/articles/s41...
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“Common gene mutations in 103 authenticated colorectal cancer cell lines”
🔵 Ragnhild A. Lothe‘s latest research is now available to read in #Oncogenesis.
▶️ Read the full open access article here: www.nature.com/articles/s41...
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“Combined Inhibition of PI3K and STAT3 signaling effectively inhibits bladder cancer growth”
🔵 Interesting research led by Yang Li was featured in #Oncogenesis.
▶️ Read the full open access article here: www.nature.com/articles/s41...
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“Human papillomavirus16 E7 enhances cell stemness by regulating the APC2/SPIN4/β-catenin axis in cervical cancer”
🔵 Shizhou Yang ‘s latest research is now available to read in #Oncogenesis.
▶️ Read the full open access article here: www.nature.com/articles/s41...
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“USP21-mediated G3BP1 stabilization accelerates proliferation and metastasis of esophageal squamous cell carcinoma via activating Wnt/β-Catenin signaling”
🔵 Interesting research led by Xiaogang Zhao has been featured in #Oncogenesis.
▶️ Read the full article here: www.nature.com/articles/s41...
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“Transcriptomic profiling of co-cultured cancer-host cells identifies hypoxia as a driver of the skeletal muscle cell’s anti-proliferative effect on cancer cells”
🔵 Jerome Ruzzin‘s latest research is available to read in #Oncogenesis.
▶️ Read the full article here: www.nature.com/articles/s41...
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This #STTT review summarizes the multifaceted role of #Microbiota in #Oncogenesis, #ImmuneModulation, and therapeutic response, discussing the emerging anti-#Cancer strategies targeting microbiota and highlighting future research directions.
#OpenAccess: doi.org/10.1038/s413...
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“Mitotic MTH1 inhibitor TH1579 induces PD-L1 expression and inflammatory response through the cGAS-STING pathway”
🔵 Interesting research led by Thomas Helleday has been featured in #Oncogenesis.
▶️ Read the full open access article here: www.nature.com/articles/s41...
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“Fatty acid uptake mediated by FABP4 promotes the formation of CD8+T cell senescence through lipid peroxidation in the adipocyte-rich microenvironment of Ovarian Cancer”
🔵 Weimin Deng ‘s research is now available to read in #Oncogenesis.
▶️ Read the full article here: www.nature.com/articles/s41...
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“The role of histone demethylase PHF2 as a tumour suppressor in hepatocellular carcinoma by regulating SRXN1”
🔵 Edward Kai-Hua Chow‘s latest research is now available to read in #Oncogenesis.
▶️ Read the full open access article here: www.nature.com/articles/s41...
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“USP32 facilitates non-small cell lung cancer progression via deubiquitinating BAG3 and activating RAF-MEK-ERK signaling pathway”
🔵 Interesting research led by Chunyan Liu has been featured in #Oncogenesis.
▶️ Read the full open access article here: www.nature.com/articles/s41...
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“Cytoskeleton reorganization induced by a novel K6-K14 keratin fusion promotes cancer stemness and cellular plasticity via cGAS-STING selection”
🔵 Jim Jinn-Chyuan Sheu‘s latest research is now available to read in #Oncogenesis.
▶️ Read the full article here: www.nature.com/articles/s41...
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“Rab37-mediated OPN secretion enriches SPP1+ macrophages through autocrine–paracrine signaling to drive lung tumor progression”
🔵 Yi-Ching Wang‘s latest research is now available to read in #Oncogenesis.
▶️ Read the full open access article here: www.nature.com/articles/s41...
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“DAB2IP inhibits glucose uptake by modulating HIF-1α ubiquitination under hypoxia in breast cancer”
🔵 Interesting research led by Jie Shen has been featured in #Oncogenesis.
▶️ Read the full open access article here: www.nature.com/articles/s41...
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“PRAS40 promotes colorectal cancer stemness by enhancing glycolysis through triggering PGK1 acetylation”
🔵Lin Huang‘s latest research is now available to read in #Oncogenesis.
▶️ Read the full open access article here: www.nature.com/articles/s41...
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“PKC-independent PI3K signalling diminishes PKC inhibitor sensitivity in uveal melanoma”
🔵 Outstanding research led by Helen Rizos has been featured in #Oncogenesis.
▶️ Read the full open access article here: www.nature.com/articles/s41...
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“Targeting mitochondrial phosphatidylethanolamine alters mitochondrial metabolism and proliferation in hepatocellular carcinoma”
🔵 Timothy D. Heden‘s latest and impressive research is now available to read in #Oncogenesis.
▶️ Read the full open access article here: www.nature.com/articles/s41...
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🚀 Join 4 connected Keystone Symposia on #CancerResearch: #Oncogenesis, #TumorMetabolism, #TumorMicroenvironment & #CancerImmunotherapy. Explore breakthroughs from molecular pathways to patients in prevention, detection, treatment & remission. 🔗 keypoint.keystonesymposia.org/home/transfo...
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“Transcriptomic analysis identifies B-lymphocyte kinase as a therapeutic target for desmoplastic small round cell tumor cancer stem cell-like cells”
🔵 Interesting research led by Sean B. Lee has been featured in #Oncogenesis.
▶️ Read the full open access article here: www.nature.com/articles/s41...
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“Dual roles of USP1 in HELLS deubiquitination and SUMOylation drive EMT and FOLFOX-based chemoresistance”
🔵 Wenjie Zheng’s latest research is now available to read in #Oncogenesis.
▶️ Read the full open access article here: www.nature.com/articles/s41...
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“An E3 ligase TRIM1 promotes colorectal cancer progression via K63-linked ubiquitination and activation of HIF1α”
🔵 Interesting research led by Kun Meng was featured in #Oncogenesis.
▶️ Read the full open access article here: www.nature.com/articles/s41...
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“Adaptation of redox metabolism in drug-tolerant persister cells is a vulnerability to prevent relapse in pancreatic cancer”
🔵 Alice Carrier’s latest and impressive research is now available to read in #Oncogenesis.
▶️ Read the full open access article here: www.nature.com/articles/s41...
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“DDX3X interacts with SIRT7 to promote PD-L1 expression to facilitate PDAC progression”
🔵 Interesting research led by Xiaoping Zou was featured in #Oncogenesis.
▶️ Read the full open access article here: www.nature.com/articles/s41...
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“Stabilization of FASN by USP5-mediated deubiquitination promotes hepatocellular carcinoma progression”
🔵Chengrong Xie’s latest research is now available to read in #Oncogenesis.
▶️ Read the full open access article here: www.nature.com/articles/s41...
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“ACSL6 modulates docosahexaenoic acid-induced cytotoxicity to potentiate chemotherapy response in colorectal and breast cancer”
🔵 Hui-Ping Hsu’s latest research is now available to read in #Oncogenesis.
▶️ Read the full open access article here: www.nature.com/articles/s41...
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