Which calcium preparation should we use in paediatric resuscitation? A comprehensive review of basic physiology, pharmacokinetics, and clinical evidence - Journal of Anesthesia, Analgesia and Critical Care Background The optimal choice between calcium gluconate (CaGN) and calcium chloride (CaCl₂) for hypocalcaemia correction during paediatric critical illness and resuscitation remains debated. This literature review aimed to compare the efficacy and safety profiles of both preparations to determine an evidence-based clinical preference. Methods A comprehensive review of in vitro, in vivo, and clinical trials involving critically ill patients was conducted, focusing on the pharmacokinetics, therapeutic efficacy (measured by the rise in ionised calcium, iCa2⁺), and comparative adverse event profiles, particularly the risk of extravasation injury. Results Both CaGN and CaCl₂ effectively correct hypocalcaemia when equivalent elemental calcium doses are administered. CaCl₂ holds a significant dosing advantage in volume-restricted or extreme emergent scenarios due to its higher concentration of elemental calcium (27.2 mg/mL vs. 9.0 mg/mL for 10% solutions). Whilst the hepatic metabolism requirement for CaGN has been widely refuted, limited paediatric data suggest CaCl₂ may yield a greater response in mean arterial pressure (MAP) in critically ill children. Crucially, the safety profile favours CaGN; a substantial body of evidence indicates that the risk and severity of tissue necrosis following extravasation are markedly higher with CaCl₂. Conclusion The selection of a calcium preparation must be conditional and context-dependent. We recommend reserving CaCl₂ for central venous administration in volume-restricted or extreme emergent settings, whilst CaGN is the preferred choice for peripheral line administration or routine maintenance due to its superior safety profile.

Ever wondered whether calcium gluconate is superior to calcium chloride in paediatric resuscitation ? Fret no more as our new paper in the Journal of Anesthesia, Analgesia and Critical Care is now out and open access .
Have a read 👇 #pedsicu #foamED

link.springer.com/article/10.1...

Sacred Spaces In this narrative medicine essay, as a pediatric critical care physician prepares to move to a new hospital building, he reflects on the memories that the old building held, including the death of his infant grandson.

Beautifully written piece by an old friend and colleague, Jim Fortenberry. Worth your time. #PedsICU HT to @sapnakmd.bsky.social
Sacred Spaces url: jamanetwork.com/journals/jam...

The latest Pediatric Critical Care Medicine issue is now available! Keep up with new research and insights to hone your practice.

Find articles on cardiac arrest, food insecurity, and sepsis, including the new Surviving Sepsis Campaign guidelines for children: pccmjournal.org

#PedsICU #SCCM

Calling all #nurses! Only 3 weeks left to apply for our Fellowship Programme that will support your participation for the upcoming #ESPNIC2026.

How to Apply 👉 bit.ly/4joTC1g
Become a member✅: bit.ly/ESPNICMember...

#NICU #PedsICU #ICUnurses #ESPNIC #CriticalCareNursing

🚨 1 Month to Go – World PICU Awareness Week 2026

🌍 Take Care of Those Who Care

May 2–8 – join the global #PedsICU community.

🎥 Share a ≤60s video on caregiver wellbeing
📲 Use #WPAW2026 & tag WFPICCS
🔗 Learn more: wfpiccs.org/2026-world-p...

Congratulations to our Division of PCCM research trainees and clinical fellows on presenting their research projects at #MCHRD @macupediatrics.bsky.social

A variety of projects spanning #PedsICU analgosedation, functional outcomes, TCD ultrasonography, and QI

Factors Associated with R01 Submission Among #PedsICU Medicine Career Development Award Recipients by the #PathwaystoIndependence @palisinet.bsky.social subgroup.

journals.lww.com/ccmjournal/a...

Happy National Doctor’s Day to all our #PedsICU Physicians !

🚨 16 April – Don’t miss the next #PRCCS webinar!

Lung Recruitment & Prone Positioning in Pediatric Ventilation

🎙 Brenda Morrow
🎙 Dr Peter Rimensberger
🕒 06:30 PM IST | 09:00 AM ET | 03:00 PM CET

🔗 Register for free: us02web.zoom.us/meeting/regi...

#PedsICU #CriticalCare

📢 Nursing Members: 1 month left to apply for our Fellowship Programme and join us at #ESPNIC2026!Be part of a community that grows together!

More info 👉 bit.ly/4joTC1g
Become a member✅: bit.ly/ESPNICMember...

#NICU #PedsICU #ICUnurses #ESPNIC #CriticalCareNursing

Communications | PALISI Network

📢📢📢 PALISI members - don't forget to submit your items for the April newsletter via www.palisi.org/communications .

Deadline for requests April 1

#PedsICU #PALISI26

As we face a (worsened) global shortage of helium, I’m curious as to how many of my #PedsICU colleagues are still routinely using Heliox for status asthmaticus.

We don’t actually know what is a “high” anti-Xa level or a “low” level is, or whether they are effective at anticoagulation in kids.
-Tony Sochet

#SCCM2026 #PedsICU

Such an incredible team! Missing our members that were unable to be present. @sccm-pediatrics.bsky.social @sccmcriticalcare.bsky.social
#PedsICU #SCCM2026

Great Simon Nadel #PedsICU

It’s almost time for #SCCM2026 congress. #PedsICU Checkout our social media to tag your posts and comments !

#PedsICU #PICS-P #Outcomes Improving care with follow-up doi.org/10.1016/j.ch...

3 days left until #ESPNIC Journal Club on Tuesday 17th March from 4PM to 5PM CET. On article: The OCTO-Plus Intervention to Support Families of Chronically Critically Ill Children in Paediatric Critical Care: A Pilot Study.

Free Registration✅: bit.ly/4d3plFk

#PedsICU #pediatrician #nicu

Happy Registered Dietician Week ! #PedsICU

1 week left to join the #ESPNIC Journal Club on Tuesday 17th March from 4PM to 5PM CET.

Free Registration✅: bit.ly/4d3plFk

#PedsICU #pediatrician #nicu #PicuNurse #intensivecareunit

Work hard, play hard. While missing a couple of our team, the #PALISI26 Executive Committee taking time to celebrate another great meeting! 👏👏👏

Safe travels everyone!

#PedsICU

@colleenmbadke.bsky.social presenting at #PALISI26 data science subgroup meeting AND being elected new vice chair of #PEDAL! #PedsICU #GoCoco

Mary Pilarz, MD presenting on interpreter use surrounding critical events in the PICU for patients and families who use a language other than English at #PALISI26 #SDOH subgroup meeting #socialdeterminantsofhealth #PedsICU

#PALISI26
#PedsICU

We had the pleasure of celebrating both our past #clinicalresearchcourse chairs and our current subgroup chairs. These leadership opportunities build networks, develop skills and move our science forward!

#PALISI26
#PedsICU

2nd year fellow Ali Austermuehle presenting at the #PALISI26 #BACON subgroup on lung protective ventilation using HFPV @palisinet.bsky.social #PedsICU #VDR with mentorship group including @colleenmbadke.bsky.social

We welcome everyone to join the #ESPNIC Journal Club on Tuesday 17th March from 4PM to 5PM CET. Don't miss the opportunity to exchange insights and experience with leading experts in #PICU care.

Free Registration✅: bit.ly/4d3plFk

#PedsICU #pediatrician #nicu #PicuNurse #intensivecareunit

#PALISI26 #PedsICU

Bria Coates, MD presenting at the #PALISI26 clinical research course on “How to be a Great Mentee and Find the Right Mentor” @palisinet.bsky.social #PedsICU

Great meeting underway at #PALISI26 in #Saltlakecity. Always pushing the envelope, always moving forward

#PedsICU