Bifunctional Lipid–Protein Cross-linking Efficiency and Reaction Products Bifunctional diazirine lipids are versatile tools for mapping protein–lipid interactions and cellular localization by photo-cross-linking. Yet, the cross-linking efficiency of these probes has not bee...

This week’s Essential Read in #chembio - my vote:

what actually happens to diazirine photolabels?

@nadlerlab.bsky.social strikes again.

Enjoy #photopharma and caveat N2or!

pubs.acs.org/doi/10.1021/...

Important paper alert #molswitches & #photopharma! Thorough, clear, fundamental mechanistics. Congratulations to @screspi.bsky.social @nadjasimeth.bsky.social and all involved!

Please folks save the date for 2nd half of September 2027 - hopefully our "Quo Vadis Photoswitches" critical meeting in Frankfurt will get the greenlight & it seems you'd belong! #molswitch #photopharma

#molswitch #photopharma

I am not self-confident enough to watch myself, but if you want to watch me present our latest work on #photopharma of #NMDA receptors, it’s here, along with other great ion channel topics 👉 sophion.com/publications...

Optochemical profiling of NMDAR molecular diversity at synaptic and extrasynaptic sites | The EMBO Journal imageimageNMDA receptors (NMDARs) play key roles in brain development and plasticity, and exist as multiple subtypes, whose individual characterization remains challenging in native tissues. This stud...

I am happy to announce the publication of our latest work on #photopharma of GluN2B NMDA receptors: www.embopress.org/doi/full/10..... I am very grateful to all the authors for their involvement in the work (@cecilecharrier.bsky.social, @cecidoso.bsky.social and all the blueskyless people). #iGluRs

Try not to have too much fun without me :) Do you mind using #photopharma and #molswitch hashtags so people in the switch/machine starter pack follow happenings?

I should also shout out Davia Prischich from my group who delivered a wonderful #photopharma #ChemBio talk on her photoswitchable peptide work.

photocontrol over high-current specific ion flows across lipid membranes can be achieved by mingling light-responsive photolipids with ion-specific carriers.

For ion-specific photocurrents across membranes: just let ionophores intermingle with photolipids.

A fully modular approach with easy access to large currents.

Stoked that this years-long sleuthing effort led by Peter Pohl is finally out! doi.org/10.1101/2025...

#photopharma #ChemBio #lipidtime

#photopharma

A great GRC #photoswitches #molmachine #photopharma

tagging for #molswitches #photopharma

📯📯NEW Chemical Biology Feed bsky.app/profile/did:...

📯List: >200 chemical biologists (probes, OC, PC, imaging): bsky.app/profile/did:...

📯Women in ChemBio Pack: bsky.app/starter-pack...

📯General #ChemBio Pack: bsky.app/starter-pack...

📯 #Photopharma: bsky.app/profile/trac...

#chemsky 🧪 🔬

attn to new #chemsky #ChemBio #realtimechem #SciSky 🧪 🔬 #photopharma community members…

#photopharma

#photopharma

📯📯Photopharmacology and Switches communities📯📯

Here is a Feed reposting #molswitch #photoswitch #photopharma

bsky.app/profile/did:...

#chemsky #chembio #scisky 🧪

Here is a Feed that reposts #molswitch #photoswitch #photopharma for tracking our community science posts - Ivan if you like it, please feel free to link it in the Pack description and add as a Recommended Feed

bsky.app/profile/did:...

#chemsky #chembio #scisky 🧪