0
0
0
0
Hashtag
#NMDA
Advertisement · 728 × 90
In the new study, OHSU researchers identified specific sites on a subunit of the #NMDA receptor that—if they could be blocked—could potentially reverse the progression of the disease. medicalxpress.com/news/2026-01-atomic-imag...
1
0
0
0
Chloe Cable, Sidney P. Kuo and Eric A. Newman observed that junctional conductance of #retinal AII amacrine cell electrical synapses is decreased by #NMDA receptors 👁️ 🧠
📜 Read the study here: physoc.onlinelibrary.wiley.com/doi/10.1113/...
5
3
0
0
Subtype-selective targeting of #NMDA receptors - A potent new compound emerges. New commentary from Hiro Furukawa @lab-furukawa.bsky.social @cshlnews.bsky.social on study work by Lotti and colleagues (rupress.org/jgp/article/...): rupress.org/jgp/article/...
1
1
0
0
Novel binding mode for negative allosteric #NMDA receptor modulators, from James Lotti, Rasmus Clausen @ucph.bsky.social, Kasper Hansen and colleagues @umontana.bsky.social: rupress.org/jgp/article/...
#MolecularPharmacology #ProteinStructure #ProteinDynamics #Biophysics
1
1
0
0
New study in @jgp.org from Lotti, Clausen, Hansen et al. @umontana.bsky.social describes a novel negative allosteric modulator that engages previously unexplored structural determinants in an allosteric binding site between #NMDA receptor subunits rupress.org/jgp/article/...
#MolecularPharmacology
0
0
0
0
New study from Lotti, Clausen, Hansen et al. @umontana.bsky.social describes a novel negative allosteric modulator that engages previously unexplored structural determinants in an allosteric binding site between #NMDA receptor subunits rupress.org/jgp/article/...
#MolecularPharmacology #Biophysics
0
0
0
0
In a recent study, Hao Xing et al. observed enhancement of #hippocampal interneuron excitability by #NMDA receptor positive allosteric modulation 🧠 🔬
📜 Read the #Research: physoc.onlinelibrary.wiley.com/doi/10.1113/...
0
0
0
0
These connections are enriched with the #NMDA receptor subunit #GRIN2D, making cancer cells more responsive to neuron-derived glutamate. Glutamate-mediated calcium influx into #CancerCells was found to trigger a signalling cascade that drives tumour growth and metastasis.
0
0
1
0
Intoxication accidentelle par l’ #ecstasy chez une enfant de 30 mois. Elle a attrapé une boîte, posée sur un petit réfrigérateur, dans laquelle sa mère rangeait des comprimés de #NMDA. Elle en a inséré un dans son nez.
www.lemonde.fr/blog/realite... [Rediff] #pediatrie #toxicologie
1
0
0
0
I am not self-confident enough to watch myself, but if you want to watch me present our latest work on #photopharma of #NMDA receptors, it’s here, along with other great ion channel topics 👉 sophion.com/publications...
7
1
0
0
Optochemical profiling of NMDAR molecular diversity at #synaptic and extrasynaptic sites
@laetitiamony.bsky.social , Pierre Paoletti and coworkers describe a method to selectively modulate the function of #NMDA receptor subunit GluN2B
www.embopress.org/doi/full/10....
1
1
0
0
Harnessing psychedelics for stroke recovery: therapeutic potential and mechanisms
#psychedelics #psilocybin #LSD #ketamine #neuroplasticity #serotonin #NMDA #stroke 🧪
doi.org/10.1093/brai...
4
0
0
0
mouse neuron in glowing orange
Insight Article: A new mode of action for unconventional NMDA receptors
Presynaptic #NMDA receptors can shape timing-dependent long-term depression in a way that departs from their classic postsynaptic role. #Neuroscience
buff.ly/cwk0rwc
11
2
0
0
1
0
0
0
#NMDA reported on 2.28 that #BirdFlu was detected in backyard poultry flock in #Bernalillo, NM. To report sick animals or unusual deaths in New Mexico, call the New Mexico State Veterinarian at 505-841-6161, USDA at 866-536-7593 or 505-313-8050, or 311 (Albuquerque/Bernalillo County residents).
1
2
1
0
1
0
0
0
This image explains the mechanism of action (MOA) of memantine in Alzheimer's disease (AD) based on the signal-to-noise hypothesis. Key Points from the Image and Caption: NMDA Receptor Dysfunction in AD: Alzheimer's pathology (e.g., Aβ, Tau, energy deficits) causes dysregulated NMDA receptor activity, leading to excessive "synaptic noise." Memantine's Role: Memantine acts as a filter blocking 'synaptic noise' by selectively blocking NMDA receptors. It helps differentiate between pathological noise and relevant synaptic signals. Restoration of Synaptic Plasticity: By filtering excessive noise, memantine allows synaptic plasticity to be restored and improves neuronal communication. Voltage-Dependent Action: Memantine preferentially blocks NMDA receptors under pathological conditions (e.g., excessive glutamate) without disrupting normal synaptic activity.
interesting drug memantine " #NMDA receptor antagonist that improves memory by restoration of homeostasis in the glutamatergic system - too little activation is bad, too much is even worse" - i.e. allows right amount of glutamatergic signal to go through www.sciencedirect.com/science/arti...
2
0
0
0
Proud moment today for many! We gathered to celebrate #science #NMDA receptors #iGluRs and the most recent doctor of phylosophy: Dr. Mae G. Weaver!
16
0
1
0
Congratulations to Pierre Paoletti who was elected at the French Academy of Sciences !
#iGluRs #NMDA
academie-sciences.prod.aa-testing.tech/sites/defaul...
9
3
1
0
Memantine‐induced functional rewiring of the glutamate synapse in the striatum of dopamine transporter knockout rats - Caffino - British Journal of Pharmacology
#openaccess
#NMDA
#ionchannels
https://buff.ly/49tOANt
1
0
0
0
Post
#ISZB-2024 meeting, sightseeing in Merida Mexico.
#science #zinc #biophysics #ionchannels #NMDA #iGluRs
3
0
0
0
Congratulations, @Elias Aizenman, for well-deserved career recognition at
#ISZB-2024 meeting in Merida Mexico.
#science #zinc #biophysics #ionchannels #NMDA #iGluRs
7
1
0
0
