#purinosome

NUDT5 regulates purine metabolism and thiopurine sensitivity by interacting with PPAT Cells generate purine nucleotides through de novo purine biosynthesis (DNPB) and purine salvage. Purine salvage represses DNPB to prevent excessive purine nucleotide synthesis through mechanisms that ...

Published last week a new paper from Ralph DeBerardinis with really cool #purinosome imaging 🧫✨

🔗 www.science.org/doi/10.1126/...

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