#Research by Kei Furukawa et al. investigates graded control of #Purkinje cell outputs by cAMP through opposing actions on axonal action potential and #transmitter release 🧠 🔬

📜 Read it here: physoc.onlinelibrary.wiley.com/doi/10.1113/...

Deletion of Endocannabinoid Synthesizing Enzyme DAGLα in Pcp2-Positive Cerebellar Purkinje Cells Decreases Depolarization-Induced Short–Term Synaptic Plasticity, Reduces Social Preference, and Heighte... The endocannabinoid (eCB) signaling system is robustly expressed in the cerebellum from embryonic developmental stages to adulthood. It plays a key role in regulating cerebellar synaptic plasticity an...

Our new research on cannabinoid signaling in cerebellar development and function is published in eNeuro.
@iupsychbrain.bsky.social #cannabinoid #cerebellum #Purkinje #DevelopmentalNeuroscience #endocannabinoid #AcademicSky #neuroskyence #Science

www.eneuro.org/content/12/7...

Purkinje cells in the cerebellum of a wild type adult mouse. One of the most beautiful cells in the body.
(by Jacob Hecksher-SørensenJacob Hecksher-Sørensen
Applying quantitative 3D imaging and spatial biology to preclinical drug development)
lnkd.in/e8QnQrZC
#neuroscience #Purkinje #cerebellum

👏 We are very proud to congratulate #neuroscientist Prof. Dr. Martijn Schonewille with his prestigious #NWO #Science #Vici #grant! For his project he aims to understand how the little #brain, the #cerebellum, controls movement by studying subgroups of #neurons ( #Purkinje cells).

🧵[1/3]

Just a gorgeous #Purkinje neuron all by itself in the cerebellum. Only with #lightsheet #microscopy on a whole #cleared sample could you ever hope to catch a lone reporter expressing cell in it’s entirety. #science 🧪

Cells in the cerebellum stained purple showing branching fibres connecting the various layers.

Histology of the cerebellum

#histology #brain #neuron #axon #purkinje #dendrite