A recent commentary by @igorbandeira.bsky.social et al. highlights the steps in clinical trial design that combine ketamine and naltrexone for major depression, allowing for a mechanistic approach.

@stanfordpsy.bsky.social
#depression #opiod #ketamine #resistantdepression #clinicaltrials

📰 #article | Combinaison odeurs plaisantes + #stimulationscérébrales dans le traitement de la #dépressionrésistante (COBRA)

🌸 Combining pleasant #Olfactory and #BRAinstimulations in treatment #resistantdepression

#depressivedisorder #olfaction #rewardsystem

pubmed.ncbi.nlm.nih.gov/39744036/