Methodologic discussions for using and interpreting composite endpoints are limited, but still identify major concerns - PubMed Methodologists have given limited attention to CEPs and their views are sometimes contradictory. Further work is needed to establish the role of CEPs in research and in guiding clinical practice.

#CompositeEndpoints frequently mislead by overestimating benefits: #death, #MyocardialInfarction (dominated), and #revascularization. Worse, add #stroke to these three and goes in opposite direction to revascularization and composite favors the wrong intervention!

pubmed.ncbi.nlm.nih.gov/17573977/

The effect of exosome-related therapy in cardiac revascularization procedures: a systematic review - BMC Cardiovascular Disorders BMC Cardiovascular Disorders - Cardiovascular diseases (CVDs) remain the leading global cause of mortality despite advances in revascularization strategies like coronary artery bypass grafting...

Exosome-based therapies show promise in cardiac #revascularization
They enhance vascular repair, reduce restenosis, and control inflammation—ushering in a new era of regenerative cardiology. #Exosomes link.springer.com/article/10.1...

📣 PCSK9 for prediction of adverse limb outcomes after endovascular #revascularization in diabetic chronic limb-threatening ischemia

📌 Biscetti et al. show that higher #PCSK9 levels linked to increased major adverse limb events among diabetic patients

🆓 on TH: www.thieme-connect.de/products/ejo...

In the randomized PROCTOR trial, SVG #PCI was assoc with improved 1-yr clinical outcomes compared with native vessel PCI, primarily driven by lower rates of PCI-related MI & clinically driven target coronary territory #revascularization https://bit.ly/4ogyuxh

#TCT2025 #JACC #cvMI #cvCABG #CardioSky

Complete vs Culprit-Only Revascularization in NSTEMI and Multivessel Disease This randomized clinical trial examines the effect of fractional flow reserve–guided complete coronary revascularization of nonculprit lesions vs culprit-only revascularization in patients with non–ST...

Revascularización completa guiada por la reserva de flujo fraccional reduce las muertes por todas las causas, IM no fatal, revascularizaciones e ictus al año, al reducir las revascularizaciones repetidas #revascularization #NSTEMI jamanetwork.com/journals/jam...

Meet Angela Zhou, a PhD candidate in Dr. @saravasconcelos.bsky.social's lab @uhn.ca and one of the 2025 Vanier Scholars.

Read about her research in #revascularization, what excites her most about being a research trainee at UHN, and her interests. ❤️‍🩹

🔗: www.uhnresearch.ca/news/angela-...

10-Year Outcome of Complete or Infarct–Artery-Only Revascularization in STEMI with Multivessel Disease (DANAMI-3-PRIMULTI):

#EuroPCR #JACC LBCT: #FFR-guided complete #revascularization reduced future and repeated events compared with infarct-related artery only after 10 years. The risk was mainly driven by revasc, with no reduction in MIs or death. www.jacc.org/doi/10.1016/... #cvMI #revasc

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How Long To Wait To Have Surgery Following A Heart Attack? The latest: heart attack victims with a post-coronary revascularization procedure should wait >3 months before undergoing any elective procedures. #heartattack #stroke #surgery #elective #revascularization
www.instagram.com/p/DCFJ4M5Mthu/

Read about the expanding population of patients living with #HIV and their specific needs when it comes to #coronary artery disease (#CAD) and #revascularization -> our new review "Coronary Revascularization in Patients with HIV

sciencedirect.com/science/articl…

Read our new review about #decision #making for #minimally #invasive and #hybrid #myocardial #revascularization! ♥️

sciencedirect.com/science/articl…