Happy to share a new way of promoting dual-atom insertion into oxetanes and azetidines to access multi-heteroatom rings using FLP chemistry, just out in @natsynth.nature.com nature.com/articles/s44... #skeletalediting #ringexpansion #FLP

Electrophilic insertion and ring growth in 1,2,5-azadiborolidines: theoretical evidence for boron-driven expansion This study computationally investigates the reactivity of 1,2,5-azadiborolidine derivatives toward carbon monoxide (CO), extending ring-expansion mechanisms from borole chemistry. Establishing structu...

Electrophilic insertion and ring growth in 1,2,5-azadiborolidines: theoretical evidence for boron-driven expansion
by Albert Poater et al.

CO insertion enables new boracycles ⚗️

doi.org/10.1039/D5QO...

#BoronChemistry #RingExpansion #ComputationalChemistry